(8S,10S)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-10-[(2S,4S,5S,6S)-5-hydroxy-6-methyl-4-(1-piperidyl)oxan-2-yl]oxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione hydrochloride

名称

[ 英文名 ]:
(8S,10S)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-10-[(2S,4S,5S,6S)-5-hydroxy-6-methyl-4-(1-piperidyl)oxan-2-yl]oxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione hydrochloride

物理化学性质

[ 沸点 ]:
829.4ºC at 760 mmHg

[ 分子式 ]:
C₃₂H₃₈ClNO₁₁

[ 分子量 ]:
648.09700

[ 闪点 ]:
455.4ºC

[ 精确质量 ]:
647.21300

[ PSA ]:
183.29000

[ LogP ]:
2.26840

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QI9427700

CHEMICAL NAME :: 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-8-(hydroxyacetyl)-1-methoxy-10-(( 2,3,6-trideoxy- 3-(1-piperidinyl)-alpha-L-lyxo-hexopyranosyl)oxy)-6,8 ,11-trihydroxy-, hydrochloride, (8S-cis)-

CAS REGISTRY NUMBER :: 70844-11-0

LAST UPDATED :: 198509

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C32-H37-N-O11.Cl-H

MOLECULAR WEIGHT :: 648.16

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Rodent - mouse Leukocyte

DOSE/DURATION :: 40 nmol/L

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 22,912,1979