O1-(7-chloro-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-β-D-glucopyranuronic acid

[ 分子式 ]:
C₂₁H₁₉ClN₂O₈

[ 分子量 ]:
462.83700

[ 精确质量 ]:
462.08300

[ PSA ]:
157.91000

[ 符号 ]:

GHS02, GHS06, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H225-H301 + H311 + H331-H370

[ 警示性声明 ]:
P210-P260-P280-P301 + P310-P311

[ 危险品运输编码 ]:
UN1230 - class 3 - PG 2 - Methanol, solution

Factors and conditions affecting the glucuronidation of oxazepam.

Pharmacol. Toxicol. 73 Suppl 1 , 1-23, (1993)

The aim of the present work was to investigate the impact of disease states and environmental and host factors on the glucuronidation of oxazepam. Glucuronidation represents quantitatively one of the ...

(S)oxazepam glucuronidation is inhibited by ketoprofen and other substrates of UGT2B7.

Pharmacogenetics 5(1) , 43-9, (1995)

1,4-Benzodiazepine anxiolytics such as diazepam and halazepam are converted in vivo to oxazepam, an active metabolite with a hydroxyl group at the asymmetric C3 position. D-glucuronic acid couples wit...

Physiological modeling of drug and metabolite: disposition of oxazepam and oxazepam glucuronides in the recirculating perfused mouse liver preparation.

J. Pharmacokinet. Biopharm. 18(5) , 423-48, (1990)

The disposition of tracer doses of 3H-oxazepam was studied in the recirculating perfused mouse liver preparation. 3H-Oxazepam was biotransformed primarily to the diastereomeric 3H-oxazepam glucuronide...

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