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二甲基砜

二甲基砜用途

Dimethyl sulfone 是一种内源性代谢产物。

二甲基砜名称

[ CAS 号 ]:
67-71-0

[ 中文名 ]:
二甲基砜

[ 英文名 ]:
Dimethyl sulfone

[中文别名 ]:

[英文别名 ]:

MFCD00007566
methylsulphonylmethane
Dimethylsulfon
MSM
Methyl sulfone
EINECS 200-665-9
Methylsulfone
METHYLSULPHONE
Sulfone,dimethyl
DIMETHYL SULPHONE

二甲基砜生物活性

[ 描述 ]:

Dimethyl sulfone 是一种内源性代谢产物。

[ 相关类别 ]:

研究领域 >> 代谢疾病

[ 靶点 ]

Human Endogenous Metabolite

二甲基砜物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
240.9±8.0 °C at 760 mmHg

[ 熔点 ]:
107-109 °C(lit.)

[ 分子式 ]:
C₂H₆O₂S

[ 分子量 ]:
94.133

[ 闪点 ]:
143.3±0.0 °C

[ 精确质量 ]:
94.008850

[ PSA ]:
42.52000

[ LogP ]:
-1.19

[ 外观性状 ]:
白色结晶片

[ 蒸汽压 ]:
0.1±0.5 mmHg at 25°C

[ 折射率 ]:
1.402

[ 储存条件 ]:
室温

[ 稳定性 ]:
Stable. Combustible. Incompatible with strong oxidizing agents.

[ 水溶解性 ]:
150 g/L (20 ºC)

二甲基砜MSDS

二甲基砜毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: PB2785000

CHEMICAL NAME :: Methane, sulfonylbis-

CAS REGISTRY NUMBER :: 67-71-0

LAST UPDATED :: 199710

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C2-H6-O2-S

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533525

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533525

二甲基砜安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xn

[ 安全声明 (欧洲) ]:
S22-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
1

[ RTECS号 ]:
PB2785000

[ 海关编码 ]:
29309070

二甲基砜合成路线

二甲基砜上下游产品

二甲基砜上游产品

二甲基砜下游产品

二甲基砜制备

由二甲基亚砜经硝酸氧化而得。将二甲基亚砜在140-145℃用硝酸氧化，反应结束后将其冷却，过滤，得白色针状结晶的粗品。再经减压蒸馏，收集138-145℃（98.42kPa）馏分即为成品。

二甲基砜海关

[ 海关编码 ]: 2904100000

[ 中文概述 ]:
2904100000 仅含磺基的衍生物及其盐和乙酯。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:5.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2904100000 derivatives containing only sulpho groups, their salts and ethyl esters。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

二甲基砜文献

Olfactometry Profiles and Quantitation of Volatile Sulfur Compounds of Swiss Tilsit Cheeses.

J. Agric. Food Chem. 63 , 7511-21, (2015)

To establish the odor profiles of three differently fabricated commercial Swiss Tilsit cheeses, analyses were conducted using headspace solid-phase microextraction gas chromatography-mass spectrometry...

The human cerebrospinal fluid metabolome

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 871(2) , 164-73, (2008)

With continuing improvements in analytical technology and an increased interest in comprehensive metabolic profiling of biofluids and tissues, there is a growing need to develop comprehensive referenc...

Methyl Sulfone Blocked Multiple Hypoxia- and Non-Hypoxia-Induced Metastatic Targets in Breast Cancer Cells and Melanoma Cells.

PLoS ONE 10 , e0141565, (2015)

Metastatic cancer causes 90% of cancer deaths. Unlike many primary tumors, metastatic tumors cannot be cured by surgery alone. Metastatic cancer requires chemotherapy. However, metastatic cells are no...

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