桑色素

桑色素用途

Morin is a yellow chemical compound that can be isolated from Maclura pomifera (Osage orange), Maclura tinctoria (old fustic) and from leaves of Psidium guajava (common guava). In a preclinical in vitro study, morin was found to be a weak inhibitor of fatty acid synthase with an IC50 of 2.33 μM. Morin was also found to inhibit amyloid formation by islet amyloid polypeptide (or amylin) and disaggregate amyloid fibers. Morin can be used to test for the presence of aluminium or tin in a solution, since it forms characteristically fluorescent coordination complexes with them.

桑色素名称

[ CAS 号 ]:
654055-01-3

[ 中文名 ]:
桑色素

[ 英文名 ]:
morin r. g.

[中文别名 ]:

[英文别名 ]:

S2325_Selleck
Morin hydrate
2',3,4',5,7-pentahydroxyflavone
Bois d,arc hydrate

桑色素物理化学性质

[ 熔点 ]:
299-300 °C (dec.)(lit.)

[ 分子式 ]:
C₁₅H₁₂O₈

[ 分子量 ]:
320.251

[ 精确质量 ]:
320.053223

[ 外观性状 ]:
yellow

[ 储存条件 ]:
室温

[ 水溶解性 ]:
methanol: soluble50mg/mL

桑色素安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi,T

[ 风险声明 (欧洲) ]:
36/37/38-25

[ 安全声明 (欧洲) ]:
26-36-45

[ 危险品运输编码 ]:
UN 2811 6.1 / PGIII

[ RTECS号 ]:
LK8749000

[ 包装等级 ]:
III

桑色素文献

A combination therapy for KRAS-driven lung adenocarcinomas using lipophilic bisphosphonates and rapamycin.

Sci. Transl. Med. 6(263) , 263ra161, (2014)

Lung cancer is the most common human malignancy and leads to about one-third of all cancer-related deaths. Lung adenocarcinomas harboring KRAS mutations, in contrast to those with EGFR and EML4-ALK mu...

Morin hydrate augments phagocytosis mechanism and inhibits LPS induced autophagic signaling in murine macrophage.

Int. Immunopharmacol. 22(2) , 356-65, (2014)

Morin, a natural flavonoid that is the primary bioactive constituent of the family Moraceae, has been found to be associated with many therapeutic properties. In this study, we evaluated the immunomod...

Drug screening boosted by hyperpolarized long-lived states in NMR.

ChemMedChem 9(11) , 2509-15, (2014)

Transverse and longitudinal relaxation times (T1ρ and T1) have been widely exploited in NMR to probe the binding of ligands and putative drugs to target proteins. We have shown recently that long-live...

更多文献

桑色素

桑色素用途

桑色素名称

桑色素物理化学性质

桑色素安全信息

桑色素文献

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