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3-硝基苯甲酰胺

3-硝基苯甲酰胺名称

[ CAS 号 ]:
645-09-0

[ 中文名 ]:
3-硝基苯甲酰胺

[ 英文名 ]:
3-NITROBENZAMIDE

[中文别名 ]:

间硝基苯甲酰胺

[英文别名 ]:

MFCD00007984
EINECS 211-431-0
3-nitrobenzamide

3-硝基苯甲酰胺物理化学性质

[ 密度 ]:
1.431g/cm3

[ 沸点 ]:
310 - 315ºC

[ 熔点 ]:
140-143 °C(lit.)

[ 分子式 ]:
C₇H₆N₂O₃

[ 分子量 ]:
166.13400

[ 闪点 ]:
145.852ºC

[ 精确质量 ]:
166.03800

[ PSA ]:
88.91000

[ LogP ]:
1.91720

[ 外观性状 ]:
黄色粉末

[ 折射率 ]:
1.618

[ 储存条件 ]:
室温

[ 稳定性 ]:
Stable. Combustible. Incompatible with strong oxidizing agents.

3-硝基苯甲酰胺MSDS

3-硝基苯甲酰胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CV5601250

CHEMICAL NAME :: Benzamide, 3-nitro-

CAS REGISTRY NUMBER :: 645-09-0

BEILSTEIN REFERENCE NO. :: 0777185

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C7-H6-N2-O3

MOLECULAR WEIGHT :: 166.15

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 28,335,1994

3-硝基苯甲酰胺安全信息

[ 风险声明 (欧洲) ]:
R22

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
CV5601250

[ 海关编码 ]:
2924299090

3-硝基苯甲酰胺合成路线

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3-硝基苯甲酰胺海关

[ 海关编码 ]: 2924299090

[ 中文概述 ]:
2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

3-硝基苯甲酰胺文献

Novel inhibitors of poly(ADP-ribose) synthetase.

Biochem. J. 185 , 775-777, (1980)

In a search for new inhibitors of the nuclear enzyme poly(ADP-ribose) synthetase, it was found that various benzamides substituted in the 3-position were the most inhibitory compounds found to date. T...

Protection by superoxide dismutase, catalase, and poly(ADP-ribose) synthetase inhibitors against alloxan- and streptozotocin-induced islet DNA strand breaks and against the inhibition of proinsulin synthesis.

J. Biol. Chem. 257(11) , 6084-8, (1982)

We have shown previously that alloxan and streptozotocin, two major diabetogenic agents, cause DNA strand breaks in rat pancreatic islets and stimulate nuclear poly(ADP-ribose) synthetase, thereby dep...

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