9-((3-(ISOPROPYLAMINO)PROPYL)AMINO)-1-NITROACRIDINE DIHYDROCHLORIDE

名称

[ CAS 号 ]:
63710-43-0

[ 英文名 ]:
9-((3-(ISOPROPYLAMINO)PROPYL)AMINO)-1-NITROACRIDINE DIHYDROCHLORIDE

物理化学性质

[ 密度 ]:
1.235g/cm3

[ 沸点 ]:
544.4ºC at 760 mmHg

[ 分子式 ]:
C₁₉H₂₃ClN₄O₂

[ 分子量 ]:
374.86500

[ 闪点 ]:
283ºC

[ 精确质量 ]:
374.15100

[ PSA ]:
82.77000

[ LogP ]:
5.88530

[ 折射率 ]:
1.674

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TX8257000

CHEMICAL NAME :: 1,3-Propanediamine, N-(1-methylethyl)-N'-(1-nitro-9-acridinyl)-, dihydrochloride

CAS REGISTRY NUMBER :: 63710-43-0

LAST UPDATED :: 198910

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C19-H22-N4-O2.2Cl-H

MOLECULAR WEIGHT :: 411.37

WISWESSER LINE NOTATION :: T C666 BNJ HNW JM3MY1&1 &GH 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 127 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - changes in motor activity (specific assay) Gastrointestinal - hypermotility, diarrhea

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 900 ug/kg

TOXIC EFFECTS :: Behavioral - changes in motor activity (specific assay)

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 126 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - changes in motor activity (specific assay) Gastrointestinal - hypermotility, diarrhea

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2170 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - changes in motor activity (specific assay) Gastrointestinal - hypermotility, diarrhea

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Bird - pigeon

DOSE/DURATION :: 2100 ug/kg

TOXIC EFFECTS :: Gastrointestinal - nausea or vomiting

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Human Lymphocyte

DOSE/DURATION :: 80 nmol/L/69H

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 67,93,1979

安全信息

[ 海关编码 ]:
2933990090

海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%