<生产厂家价格>

甲酰肼

甲酰肼用途

用于有机合成。

甲酰肼名称

[ CAS 号 ]:
624-84-0

[ 中文名 ]:
甲酰肼

[ 英文名 ]:
formohydrazide

[中文别名 ]:

甲酸肼

[英文别名 ]:

MFCD00007589
Formic hydrazide
formohydrazide
formic acid hydrazide
Hydrazine, formyl-
EINECS 210-867-9

甲酰肼物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
129.7±23.0 °C at 760 mmHg

[ 熔点 ]:
52-57 °C(lit.)

[ 分子式 ]:
CH₄N₂O

[ 分子量 ]:
60.055

[ 闪点 ]:
32.2±22.6 °C

[ 精确质量 ]:
60.032364

[ PSA ]:
55.12000

[ LogP ]:
-2.05

[ 外观性状 ]:
白色有光泽的结晶片

[ 蒸汽压 ]:
10.0±0.2 mmHg at 25°C

[ 折射率 ]:
1.424

[ 储存条件 ]:
2-8°C

[ 水溶解性 ]:
Soluble

甲酰肼MSDS

甲酰肼毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LQ8615000

CHEMICAL NAME :: Formic acid, hydrazide

CAS REGISTRY NUMBER :: 624-84-0

BEILSTEIN REFERENCE NO. :: 0635759

LAST UPDATED :: 199701

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C-H4-N2-O

MOLECULAR WEIGHT :: 60.07

WISWESSER LINE NOTATION :: ZMVH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 120 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 18,645,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 65 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC) V.1-5, 1959-62. For publisher information, see JMCMAR. Volume(issue)/page/year: 4,259,1961 ** TUMORIGENIC DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 73 gm/kg/43W-C

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors

REFERENCE :: BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 37,960,1978 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4064 No. of Facilities: 17 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 919 (estimated) No. of Female Employees: 306 (estimated)

甲酰肼安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn:Harmful;

[ 风险声明 (欧洲) ]:
R20/21/22;R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36-S36/37/39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
LQ8615000

[ 海关编码 ]:
2928000090

甲酰肼合成路线

甲酰肼上下游产品

甲酰肼上游产品

甲酰肼下游产品

甲酰肼制备

由甲酸乙酯与水合肼反应则得。将85%水合肼小心地加入甲酸乙酯和95%乙醇的溶液中，搅拌10min。当反应缓和后，将反应液加热回流18h，减压蒸出大部分水分和乙醇，即得糖浆状物粗品，进一步精制得到甲酰肼成品。

甲酰肼海关

[ 海关编码 ]: 2928000090

[ 中文概述 ]:
2928000090 其他肼（联氨）及胲（羟胺）的有机衍生物。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

甲酰肼文献

N-ethyl-N-formylhydrazine tumorigenesis in mice.

Carcinogenesis 1(1) , 61-5, (1980)

N-ethyl-N-formylhydrazine (EFH) was administered as a 0.02% solution in drinking water continuously for life to randomly bred Swiss mice, from 6 weeks of age. The treatment induced tumors of the lungs...

Traceless liquid-phase synthesis of 3-alkylamino-4, 5-disubstituted-1, 2, 4-triazoles on polyethylene glycol (PEG). Zong Y-X, et al.

Tetrahedron Lett. 46(31) , 5139-41, (2005)

Synthesis of NB-506, a new anticancer agent. Ohkubo M, et al.

Tetrahedron 53(2) , 585-92, (1997)

更多文献

甲酰肼