硫脲
硫脲用途
用于制造磺胺药物、染料、树脂、压塑粉等,也用作橡胶的硫化促进剂、金属矿物的浮选剂等
【用途二】
用作分析试剂、络合指示剂及色层分析试剂
【用途三】
硫脲是杀菌剂拌种灵,除草剂乙草胺、特草津等的中间体,也是医药硫胺噻唑的原料,并可作为染料、树脂、压塑粉的原料,也可作橡胶的硫化促进剂、金属矿物的浮选剂等。
【用途四】
医药上用作生产药物的中间体。橡胶工业上用作硫化促进剂。采矿业上用作浮选剂。还用作织物、纸张处理剂,印染助剂。
【用途五】
本品用以合成磺胺噻唑、蛋氨酸和肥猪片等药物的原料。用作染料及染色助剂、树脂及压塑粉的原料。也可用作橡胶的硫化促进剂、金属矿物的浮选剂、制邻苯二甲酸酐和富马酸的催化剂,以及用作金属防锈蚀剂。在照相材料方面,可作为显影剂和调色剂。还可用于电镀工业。硫脲还用于重氮感光纸、合成树脂涂料、阴离子交换树脂、发芽促进剂、杀菌剂等许多方面。硫脲也作为化肥使用。
【用途六】
还原剂。铅、铊、镉的沉淀 剂。检定和测定铋、饿、钌、硒、铅、碲、钯和亚硒酸盐。有机合成,由卤烷制备硫醇。
硫脲名称
[ CAS 号 ]:
62-56-6
[ 中文名 ]:
硫脲
[ 英文名 ]:
Thiourea
[中文别名 ]:
[英文别名 ]:
- THU
- thiouree
- Tsizp 34
- Sulourea
- Thiocarbamidsaeure-amid
- carbamimidothioic acid
- EINECS 200-543-5
- 250g
- Thiurea
- Isothioharnstoff
硫脲物理化学性质
[ 密度 ]:
1.405
[ 沸点 ]:
186.8±23.0 °C at 760 mmHg
[ 熔点 ]:
171-175 ºC
[ 分子式 ]:
CH4N2S
[ 分子量 ]:
76.121
[ 闪点 ]:
66.8±22.6 °C
[ 精确质量 ]:
76.009521
[ PSA ]:
84.13000
[ LogP ]:
-1.05
[ 外观性状 ]:
白色晶体
[ 蒸汽压 ]:
0.7±0.4 mmHg at 25°C
[ 折射率 ]:
1.654
[ 储存条件 ]:
库房通风低温干燥,与食品原料分开储运
[ 稳定性 ]:
Stable. Incompatible with strong acids, strong bases, strong oxidizing agents, metallic salts, proteins, hydrocarbons. May react violently with acrolein.
[ 水溶解性 ]:
13.6 g/100 mL (20 ºC)
硫脲MSDS
硫脲毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YU2800000
- CHEMICAL NAME :
- Urea, 2-thio-
- CAS REGISTRY NUMBER :
- 62-56-6
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 64
- MOLECULAR FORMULA :
- C-H4-N2-S
- MOLECULAR WEIGHT :
- 76.13
- WISWESSER LINE NOTATION :
- ZYZUS
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - woman
- DOSE/DURATION :
- 1660 mg/kg/5W
- TOXIC EFFECTS :
- Blood - hemorrhage Blood - granulocytopenia Blood - changes in cell count (unspecified)
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Human - man
- DOSE/DURATION :
- 147 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 125 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 436 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 6985 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 4 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Amphibian - frog
- DOSE/DURATION :
- 10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 3500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2550 mg/kg/5W-C
- TOXIC EFFECTS :
- Endocrine - changes in thyroid weight
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 25 mg/m3/17W-I
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay) Endocrine - evidence of thyroid hypofunction Related to Chronic Data - changes in prostate weight
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 47200 ug/m3/39W-I
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - emphysema Lungs, Thorax, or Respiration - chronic pulmonary edema Endocrine - changes in thyroid weight
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 78 gm/kg/56W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Sense Organs and Special Senses (Eye) - tumors Sense Organs and Special Senses (Ear) - effect, not otherwise specified
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Multiple routes
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 151 gm/kg/52W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Sense Organs and Special Senses (Eye) - tumors Sense Organs and Special Senses (Ear) - effect, not otherwise specified
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 18 gm/kg/2Y-C
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Liver - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 40 gm/kg/2Y-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1950 mg/kg/2Y-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - multiple effects Lungs, Thorax, or Respiration - other changes
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Multiple routes
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 179 gm/kg/1Y-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 90 gm/kg/1Y-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Endocrine - thyroid tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 240 mg/kg
- SEX/DURATION :
- female 12 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - Central Nervous System Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1 gm/kg
- SEX/DURATION :
- female 12 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1400 mg/kg
- SEX/DURATION :
- female 16-22 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - endocrine system
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 4800 mg/kg
- SEX/DURATION :
- female 17-22 day(s) after conception lactating female 10 day(s) post-birth
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1 gm/kg
- SEX/DURATION :
- female 10 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 22400 mg/kg
- SEX/DURATION :
- female 10 week(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - uterus, cervix, vagina Reproductive - Maternal Effects - other effects
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 9 gm/kg
- SEX/DURATION :
- male 90 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Paternal Effects - other effects on male
MUTATION DATA
- TYPE OF TEST :
- Mutation in mammalian somatic cells
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 10 mmol/L
- REFERENCE :
- ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 58,5,1985 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 7,95,1974 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 7,95,1974 IARC Cancer Review:Group 2B IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 TOXICOLOGY REVIEW 85CVA2 "Oncology 1970, Proceedings of the Tenth International Cancer Congress," Chicago, Year Book Medical Pub., 1971 Volume(issue)/page/year: 5,250,1970 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-FINLAND;Carcinogen JAN 1993 OEL-FRANCE;Carcinogen JAN 1993 OEL-GERMANY;Carcinogen JAN 1993 OEL-RUSSIA:STEL 0.3 mg/m3 JAN 1993 OEL-SWEDEN;Carcinogen JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82272 No. of Facilities: 1179 (estimated) No. of Industries: 29 No. of Occupations: 25 No. of Employees: 12517 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 82272 No. of Facilities: 2999 (estimated) No. of Industries: 50 No. of Occupations: 57 No. of Employees: 37571 (estimated) No. of Female Employees: 10969 (estimated)
硫脲安全信息
[ 符号 ]:
GHS07, GHS08, GHS09
[ 信号词 ]:
Warning
[ 危害声明 ]:
H302-H351-H361d-H411
[ 警示性声明 ]:
P201-P273-P301 + P312 + P330-P308 + P313-P391-P501
[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ 危害码 (欧洲) ]:
Xn:Harmful
[ 风险声明 (欧洲) ]:
R22;R40;R51/53;R63
[ 安全声明 (欧洲) ]:
S36/37-S61
[ 危险品运输编码 ]:
UN 2811 6.1/PG 3
[ WGK德国 ]:
2
[ RTECS号 ]:
YU2800000
[ 包装等级 ]:
III
[ 危险类别 ]:
6.1
[ 海关编码 ]:
2930909090
硫脲合成路线
硫脲上下游产品
硫脲上游产品
硫脲下游产品
硫脲制备
硫脲海关
[ 海关编码 ]: 2930909090
[ 中文概述 ]:
2930909090. 其他有机硫化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
[ 申报要素 ]: 品名, 成分含量, 用途
[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
硫脲文献
Autophagy 10(7) , 1241-55, (2014)
Glioblastoma is one of the most aggressive human cancers with poor prognosis, and therefore a critical need exists for novel therapeutic strategies for management of glioblastoma patients. Itraconazol...
Comparison of the antifungal efficacy of terbinafine hydrochloride and ciclopirox olamine containing formulations against the dermatophyte Trichophyton rubrum in an infected nail plate model.Mol. Pharm. 11(7) , 1991-6, (2014)
Onychomycosis is a fungal infection mostly induced by dermatophytes such as Trichophyton rubrum. Due to slow nail growth, the treatment takes 3-9 months depending on the nail size and infected area. H...
H4 histamine receptors inhibit steroidogenesis and proliferation in Leydig cells.J. Endocrinol. 223(3) , 241-53, (2014)
The histamine H4 receptor (HRH4), discovered only 13 years ago, is considered a promising drug target for allergy, inflammation, autoimmune disorders and cancer, as reflected by a steadily growing num...
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推荐生产厂家/供应商:
公司名:上海吉至生化科技有限公司
区域:上海市奉贤区
价格:
¥68.0/500g
¥48.0/25g
联系人:刘佳
产品详情:硫脲
公司名:上海阿拉丁生化科技股份有限公司
区域:上海市浦东新区
价格:
¥79.0/500g
¥需询单/1g
¥31.0/100g
¥需询单/1g
联系人:阿拉丁李高志
产品详情:硫脲
公司名:济南创世化工有限公司
区域:济南市天桥区
价格:
¥需询单/25kg
联系人:严玲玲
产品详情:硫脲
公司名:中山市迪欣化工有限公司
区域:中山市三角镇
价格:
¥20.0/1000kg
联系人:王洁
产品详情:硫脲
公司名:山东金悦源新材料有限公司
区域:济南市天桥区
价格:
¥300.0/25kg
¥11000.0/1ton
联系人:王思兵
产品详情:硫脲
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相关化合物
【硫脲】化源网提供硫脲CAS号62-56-6,硫脲MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询硫脲上化源网,专业又轻松。>>电脑版:硫脲
标题:硫脲_MSDS_用途_密度_硫脲CAS号【62-56-6】_化源网 地址:https://www.chemsrc.com/amp/cas/62-56-6_820566.html