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2-氯喹啉

2-氯喹啉名称

[ CAS 号 ]:
612-62-4

[ 中文名 ]:
2-氯喹啉

[ 英文名 ]:
Chloroquinoline

[英文别名 ]:

2-Chloroquinoline 1GR
2CQ
Chloroquinoline
2-Chlor-chinolin
2-chloro-quinoline
Quinoline, 2-chloro-
EINECS 210-317-8
quinolyl chloride
Quinoline2-chloro
2-chloro-quinolin

2-氯喹啉物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
267.3±13.0 °C at 760 mmHg

[ 熔点 ]:
34-37 °C(lit.)

[ 分子式 ]:
C₉H₆ClN

[ 分子量 ]:
163.604

[ 闪点 ]:
141.2±5.4 °C

[ 精确质量 ]:
163.018875

[ PSA ]:
12.89000

[ LogP ]:
2.71

[ 外观性状 ]:
淡灰色白色结晶粉末

[ 蒸汽压 ]:
0.0±0.5 mmHg at 25°C

[ 折射率 ]:
1.652

[ 储存条件 ]:
0-10°C;存放于惰性气体之中;避免空气,加热

[ 水溶解性 ]:
Insoluble

2-氯喹啉MSDS

2-氯喹啉毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VB2320000

CHEMICAL NAME :: Quinoline, 2-chloro-

CAS REGISTRY NUMBER :: 612-62-4

BEILSTEIN REFERENCE NO. :: 0112561

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C9-H6-Cl-N

MOLECULAR WEIGHT :: 163.61

2-氯喹啉安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36-S37/39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
VB2320000

[ 海关编码 ]:
2933499090

2-氯喹啉合成路线

2-氯喹啉上下游产品

2-氯喹啉上游产品

2-氯喹啉下游产品

2-氯喹啉海关

[ 海关编码 ]: 2933499090

[ 中文概述 ]:
2933499090. 其他含喹琳或异喹啉环系的化合物〔但未进一步稠合的〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

2-氯喹啉文献

Antiprotozoal activity of chloroquinoline based chalcones.

Eur. J. Med. Chem. 46 , 1897-905, (2011)

A new series of chloroquinoline based chalcones were synthesized and evaluated for in vitro antiamoebic and antimalarial activities. The results showed that out of fifteen compounds, four were found t...

Ruthenium-catalyzed cyclization of anilides with substituted propiolates or acrylates: an efficient route to 2-quinolinones.

Org. Lett. 16(13) , 3568-71, (2014)

A Ru-catalyzed cyclization of anilides with propiolates or acrylates affording 2-quinolinones having diverse functional groups in good to excellent yields is described. Later, 2-quinolinones were conv...

Chemoenzymatic synthesis of chiral 2,2'-bipyridine ligands and their N-oxide derivatives: applications in the asymmetric aminolysis of epoxides and asymmetric allylation of aldehydes.

Org. Biomol. Chem. 8(5) , 1081-90, (2010)

A series of enantiopure 2,2'-bipyridines have been synthesised from the corresponding cis-dihydrodiol metabolites of 2-chloroquinolines. Several of the resulting hydroxylated 2,2'-bipyridines were fou...

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