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1,3-茚满二酮

1,3-茚满二酮用途

三、用途

用作有机合成试剂。

1,3-茚满二酮名称

[ CAS 号 ]:
606-23-5

[ 中文名 ]:
1,3-茚满二酮

[ 英文名 ]:
1,3-INDANDIONE

[中文别名 ]:

[英文别名 ]:

1,3-INDANDIONE
MFCD00003779
1H-Indene-1,3(2H)-dione
1,3-Indanedione
EINECS 210-109-7

1,3-茚满二酮物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
302.5±22.0 °C at 760 mmHg

[ 熔点 ]:
129-132 °C(lit.)

[ 分子式 ]:
C₉H₆O₂

[ 分子量 ]:
146.143

[ 闪点 ]:
113.0±19.3 °C

[ 精确质量 ]:
146.036774

[ PSA ]:
34.14000

[ LogP ]:
1.14

[ 外观性状 ]:
米色至棕色粉末

[ 蒸汽压 ]:
0.0±0.6 mmHg at 25°C

[ 折射率 ]:
1.610

[ 储存条件 ]:
室温

1,3-茚满二酮MSDS

1,3-茚满二酮毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NK5070000

CHEMICAL NAME :: 1,3-Indandione

CAS REGISTRY NUMBER :: 606-23-5

BEILSTEIN REFERENCE NO. :: 1210061

LAST UPDATED :: 199709

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C9-H6-O2

MOLECULAR WEIGHT :: 146.15

WISWESSER LINE NOTATION :: L56 BV DV CHJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 33,191,1975 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 25 mg/kg

SEX/DURATION :: female 9 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - musculoskeletal system

REFERENCE :: ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 33,191,1975

1,3-茚满二酮安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R33

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
NK5070000

[ 包装等级 ]:
II; III

[ 危险类别 ]:
4.1

[ 海关编码 ]:
29143900

1,3-茚满二酮合成路线

1,3-茚满二酮上下游产品

1,3-茚满二酮上游产品

1,3-茚满二酮下游产品

1,3-茚满二酮制备

1.生产方法简述

由邻苯二甲酸二乙酯和乙酸乙酯在乙醇钠作用下缩合，然后用稀酸水解制得。

2.制法：

于装有搅拌器、滴液漏斗、回流冷凝器（安装氯化钙干燥管）的反应瓶中，加入邻苯二甲酸二乙酯（2）125g（0.563mol），金属钠丝25g（1.09mol），蒸汽浴加热。滴加由干燥的乙酸乙酯122.5g（1.39mol）和2.5mL无水乙醇配成的混合液，约1.5h加完，而后继续搅拌反应6h。冷却，加入乙醚50mL。过滤析出的钠盐，以乙酸乙酯洗涤。将钠盐溶于1.5L热水中，冷却至70℃，剧烈搅拌下加入100mL硫酸（由3份硫酸和1份水组成）。冰水浴冷却至15℃。抽滤，水洗，于100℃干燥，得1,3-茚二酮（1）58g，收率71%。用二氧六环-苯重结晶（加入石油醚），mp130℃。

1,3-茚满二酮海关

[ 海关编码 ]: 2914399090

[ 中文概述 ]:
2914399090. 其他不含其他含氧基的芳香酮. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:5.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 丙酮报明包装

[ Summary ]:
2914399090. other aromatic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

1,3-茚满二酮文献

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