GNF-1331

GNF-1331 is a Potent, Selective, and Orally Bioavailable Porcupine Inhibitor (IC50 = 12 nM). Blockade of aberrant Wnt signaling is an attractive therapeutic approach in multiple cancers. Wnt signaling is tightly controlled during cellular proliferation, differentiation, and embryonic morphogenesis. Aberrant activation of this pathway plays a critical role in a variety of cancers, such as cutaneous squamous cell carcinoma (SCC), breast cancer, and colorectal cancer.

[ 密度 ]:
1.4±0.1 g/cm3

[ 分子式 ]:
C₂₀H₂₀N₆O₂S₂

[ 分子量 ]:
440.542

[ 精确质量 ]:
440.108917

[ LogP ]:
4.35

[ 折射率 ]:
1.724

公司名：上海源溪生物科技有限公司

区域：上海市浦东新区

价格：
￥需询单/1g

联系人：赖经理

产品详情：GNF-1331

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