2-(Alpha-环戊基-alpha-2-噻吩羟基乙酰基氧基)乙基二乙基(甲基)溴化铵

名称

[ CAS 号 ]:
60-44-6

[ 中文名 ]:
2-(Alpha-环戊基-alpha-2-噻吩羟基乙酰基氧基)乙基二乙基(甲基)溴化铵

[ 英文名 ]:
Ethanaminium,2-[[2-cyclopentyl-2-hydroxy-2-(2-thienyl)acetyl]oxy]-N,N-diethyl-N-methyl-,bromide (1:1)

[英文别名 ]:

Penthienate
PENTHIENATE BROMIDE
Monodral bromide
WIN 4369
EINECS 200-478-2

物理化学性质

[ 分子式 ]:
C₁₈H₃₀BrNO₃S

[ 分子量 ]:
420.40500

[ 精确质量 ]:
419.11300

[ PSA ]:
74.77000

[ LogP ]:
0.15950

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BP7525000

CHEMICAL NAME :: Ammonium, diethyl(2-hydroxyethyl)methyl-, bromide, alpha-cyclopentyl-2-thiopheneglycolate

CAS REGISTRY NUMBER :: 60-44-6

LAST UPDATED :: 199109

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C18-H30-N-O3-S.Br

MOLECULAR WEIGHT :: 420.46

WISWESSER LINE NOTATION :: T5SJ BXQVO2K2&2&1&- AL5TJ &Q &E

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2080 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 110,282,1954

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 350 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CLDND* Compilation of LD50 Values of New Drugs. (J.R. MacDougal, Dept. of National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa, Ont., Canada)

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 16 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 110,282,1954

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 99 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1849- Volume(issue)/page/year: 151,614,1957