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二氢麦角胺(+)-酒石酸盐

二氢麦角胺(+)-酒石酸盐用途

用于生化研究。抗偏头痛药。

二氢麦角胺(+)-酒石酸盐名称

[ CAS 号 ]:
5989-77-5

[ 中文名 ]:
双氢麦角胺酒石酸盐

[ 英文名 ]:
dihydroergotamine tartrate

[英文别名 ]:

MFCD00050969
9,10-dihydroergotaminetartrate
Dihydroergotamintartrat
DIHYDROERGOTAMINE TARTRATE CRYSTALLINE
dihydro-ergotamintartrate(2:1)(salt)
DIHYDROERGOTAMINETARTRATE[DD]

二氢麦角胺(+)-酒石酸盐物理化学性质

[ 沸点 ]:
899.5ºC at 760 mmHg

[ 分子式 ]:
C₇₀H₈₀N₁₀O₁₆

[ 分子量 ]:
1317.44000

[ 闪点 ]:
497.8ºC

[ 精确质量 ]:
1316.58000

[ PSA ]:
351.48000

[ LogP ]:
2.44880

[ 折射率 ]:
-55 ° (C=1, Pyridine)

[ 水溶解性 ]:
Very slightly soluble in water, sparingly soluble in alcohol

二氢麦角胺(+)-酒石酸盐MSDS

详细MSDS(安全技术说明书)

二氢麦角胺(+)-酒石酸盐毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KE8000000

CAS REGISTRY NUMBER :: 5989-77-5

LAST UPDATED :: 199712

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C66-H74-N10-O10.C4-H6-O6

MOLECULAR WEIGHT :: 1317.60

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 110 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BSAMA5 Bulletin der Schweizerischen Akademie der Medizinischen Wissenschaften. (Schwabe & Co., Steinentorstr. 13, CH-4010 Basel, Switzerland) V.1- 1944- Volume(issue)/page/year: 2,1,1946/1947

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 210 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: RPOBAR Research Progress in Organic-Biological and Medicinal Chemistry. (New York, NY) V.1-3, 1964-72. Discontinued. Volume(issue)/page/year: 2,284,1970

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 118 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BSAMA5 Bulletin der Schweizerischen Akademie der Medizinischen Wissenschaften. (Schwabe & Co., Steinentorstr. 13, CH-4010 Basel, Switzerland) V.1- 1944- Volume(issue)/page/year: 2,1,1946/1947

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 68 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BSAMA5 Bulletin der Schweizerischen Akademie der Medizinischen Wissenschaften. (Schwabe & Co., Steinentorstr. 13, CH-4010 Basel, Switzerland) V.1- 1944- Volume(issue)/page/year: 2,1,1946/1947

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 25 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BSAMA5 Bulletin der Schweizerischen Akademie der Medizinischen Wissenschaften. (Schwabe & Co., Steinentorstr. 13, CH-4010 Basel, Switzerland) V.1- 1944- Volume(issue)/page/year: 2,1,1946/1947

二氢麦角胺(+)-酒石酸盐安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H312-H332

[ 警示性声明 ]:
P280

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn

[ 风险声明 (欧洲) ]:
20/21/22

[ 安全声明 (欧洲) ]:
36

[ 危险品运输编码 ]:
UN 1544

[ WGK德国 ]:
3

[ RTECS号 ]:
KE8000000

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1(b)