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2-噻吩甲酰胺

2-噻吩甲酰胺名称

[ CAS 号 ]:
5813-89-8

[ 中文名 ]:
2-噻吩甲酰胺

[ 英文名 ]:
2-Thiophenecarboxamide

[中文别名 ]:

[英文别名 ]:

2-thiophenecarboxamide
MFCD00010425
EINECS 238-028-2

2-噻吩甲酰胺物理化学性质

[ 密度 ]:
1.302g/cm3

[ 沸点 ]:
313.5ºC at 760 mmHg

[ 熔点 ]:
181-183 °C(lit.)

[ 分子式 ]:
C₅H₅NOS

[ 分子量 ]:
127.16400

[ 闪点 ]:
143.4ºC

[ 精确质量 ]:
127.00900

[ PSA ]:
71.33000

[ LogP ]:
1.54730

[ 外观性状 ]:
固体;White to Almost white powder to crystal

[ 折射率 ]:
1.603

[ 储存条件 ]:
室温

2-噻吩甲酰胺MSDS

2-噻吩甲酰胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XM8290000

CHEMICAL NAME :: 2-Thiophenecarboxamide

CAS REGISTRY NUMBER :: 5813-89-8

BEILSTEIN REFERENCE NO. :: 0110153

LAST UPDATED :: 199706

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C5-H5-N-O-S

MOLECULAR WEIGHT :: 127.17

WISWESSER LINE NOTATION :: T5SJ BVZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 85 mg/kg

TOXIC EFFECTS :: Behavioral - muscle weakness Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 19,449,1961

2-噻吩甲酰胺安全信息

[ 危害码 (欧洲) ]:
Xn,Xi

[ 风险声明 (欧洲) ]:
36/37/38-20/21/22

[ 安全声明 (欧洲) ]:
S36/37/39-S26-S22

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
XM8290000

[ 海关编码 ]:
2934999090

2-噻吩甲酰胺合成路线

2-噻吩甲酰胺上下游产品

2-噻吩甲酰胺上游产品

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2-噻吩甲酰胺海关

[ 海关编码 ]: 2934999090

[ 中文概述 ]:
2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

2-噻吩甲酰胺文献

A novel reaction mediated by human aldehyde oxidase: amide hydrolysis of GDC-0834.

Drug Metab. Dispos. 43 , 908-15, (2015)

GDC-0834, a Bruton's tyrosine kinase inhibitor investigated as a potential treatment of rheumatoid arthritis, was previously reported to be extensively metabolized by amide hydrolysis such that no mea...

BDNF-TrkB signaling in the nucleus accumbens shell of mice has key role in methamphetamine withdrawal symptoms.

Transl. Psychiatry 5 , e666, (2015)

Depression is a core symptom of methamphetamine (METH) withdrawal during the first several weeks of abstinence. However, the precise mechanisms underlying METH withdrawal symptoms remain unknown. Brai...

Disruption of microtubules sensitizes the DNA damage-induced apoptosis through inhibiting nuclear factor κB (NF-κB) DNA-binding activity.

J. Korean Med. Sci. 25 , 1574-81, (2010)

The massive reorganization of microtubule network involves in transcriptional regulation of several genes by controlling transcriptional factor, nuclear factor-kappa B (NF-κB) activity. The exact mole...

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