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L-胱硫醚

L-胱硫醚用途

L-Cystathionine 是一种关键的非蛋白质氨基酸。

L-胱硫醚名称

[ CAS 号 ]:
56-88-2

[ 中文名 ]:
L-胱硫醚

[ 英文名 ]:
L-Cystathionine

[英文别名 ]:

L-Cystathionine
EINECS 200-295-8
D-Homocysteine, S-[(2R)-2-amino-2-carboxyethyl]-
S-[(2R)-2-Amino-2-carboxyethyl]-D-homocysteine
(Quinoxalin-6-yl)methanamine hydrochloride
MFCD00036685

L-胱硫醚生物活性

[ 描述 ]:

L-Cystathionine 是一种关键的非蛋白质氨基酸。

[ 相关类别 ]:

天然产物 >> 其他

研究领域 >> 其他

[ 靶点 ]

Human Endogenous Metabolite

[体外研究]

L-胱硫醚是哺乳动物组织中L-甲硫氨酸通过L-高半胱氨酸的L-半胱氨酸转硫途径中的重要代谢中间体[1]。

[参考文献]

[1]. Amino Y, et al. Synthesis and evaluation of L-cystathionine as a standard for amino acid analysis. Biosci Biotechnol Biochem. 2017 Jan;81(1):95-101.

[相关活性小分子]

L-胱硫醚物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
481.0±45.0 °C at 760 mmHg

[ 熔点 ]:
312ºC

[ 分子式 ]:
C₇H₁₄N₂O₄S

[ 分子量 ]:
222.262

[ 闪点 ]:
244.7±28.7 °C

[ 精确质量 ]:
222.067429

[ PSA ]:
151.94000

[ LogP ]:
-0.13

[ 外观性状 ]:
白色结晶固体

[ 蒸汽压 ]:
0.0±2.6 mmHg at 25°C

[ 折射率 ]:
1.592

[ 储存条件 ]:
-20°C，密闭，干燥

L-胱硫醚MSDS

L-胱硫醚安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

L-胱硫醚合成路线

L-胱硫醚上下游产品

L-胱硫醚上游产品

L-胱硫醚下游产品

L-胱硫醚制备

由邻琥珀酰高丝氨酸与半胱氨酸作用生成。胱硫醚被胱硫醚β-裂解酶作用脱去丙酮酸和NH3后生成高半胱氨酸。

L-胱硫醚文献

Physiology and pathophysiology of organic acids in cerebrospinal fluid.

J. Inherit. Metab. Dis. 16(4) , 648-69, (1993)

Concentrations of organic acids in cerebrospinal fluid (CSF) appear to be directly dependent upon their rate of production in the brain. There is evidence that the net release of short-chain monocarbo...

Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression.

Nature 457(7231) , 910-4, (2009)

Multiple, complex molecular events characterize cancer development and progression. Deciphering the molecular networks that distinguish organ-confined disease from metastatic disease may lead to the i...

Automated screening of urine samples for carbohydrates, organic and amino acids after treatment with urease.

J. Chromatogr. A. 562(1-2) , 125-38, (1991)

Eighty-five clinical urine samples and nineteen urine samples previously found by other laboratories to suggest genetic metabolic defects were prepared for trimethylsilylation by treatment with urease...

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