非尼拉朵
非尼拉朵名称
[ CAS 号 ]:
553-69-5
[ 中文名 ]:
非尼拉朵
[ 英文名 ]:
Benzenemethanol, a-[(2-pyridinylamino)methyl]-
[中文别名 ]:
[英文别名 ]:
- Miodar
- Vilexin
- 1-phenyl-2-pyridin-2-ylamino-ethanol
- Analexin
- Cabral
- Evasprine
- MJ 505
- IN 511
- Abbolexin
- Bonapar
非尼拉朵物理化学性质
[ 密度 ]:
1.206g/cm3
[ 沸点 ]:
383.2ºC at 760mmHg
[ 分子式 ]:
C13H14N2O
[ 分子量 ]:
214.26300
[ 闪点 ]:
185.5ºC
[ 精确质量 ]:
214.11100
[ PSA ]:
45.15000
[ LogP ]:
2.30010
[ 折射率 ]:
1.647
非尼拉朵毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DP1050000
- CHEMICAL NAME :
- Benzyl alcohol, alpha-((2-pyridylamino)methyl)-
- CAS REGISTRY NUMBER :
- 553-69-5
- BEILSTEIN REFERENCE NO. :
- 0169969
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C13-H14-N2-O
- MOLECULAR WEIGHT :
- 214.29
- WISWESSER LINE NOTATION :
- T6NJ BM1YQR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 756 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - antipsychotic Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 130,280,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1850 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 103,245,1964
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 355 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - antipsychotic Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 141,83,1963
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 405 mg/kg
- TOXIC EFFECTS :
- Behavioral - anticonvulsant
- REFERENCE :
- APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 19,247,1962
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 124 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 141,83,1963
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