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Siastatin B microbial

Siastatin B microbial名称

[ CAS 号 ]:
54795-58-3

[ 英文名 ]:
Siastatin B microbial

[英文别名 ]:

Siastatin B microbial物理化学性质

[ 密度 ]:
1.48g/cm3

[ 沸点 ]:
579.2ºC at 760 mmHg

[ 分子式 ]:
C₈H₁₄N₂O₅

[ 分子量 ]:
218.20700

[ 闪点 ]:
304.1ºC

[ 精确质量 ]:
218.09000

[ PSA ]:
118.89000

[ 折射率 ]:
1.581

Siastatin B microbialMSDS

Siastatin B microbial毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TM6125400

CHEMICAL NAME :: 3-Piperidinecarboxylic acid, 6-(acetylamino)-4,5-dihydroxy-, (3S-(3-alpha,4-alpha,5-alpha,6- beta))-

CAS REGISTRY NUMBER :: 54795-58-3

LAST UPDATED :: 199206

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C8-H14-N2-O5

MOLECULAR WEIGHT :: 218.24

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >125 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 27,963,1974

Siastatin B microbial安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi

[ 危险品运输编码 ]:
NONH for all modes of transport

[ RTECS号 ]:
TM6125400

[ 海关编码 ]:
2933399090

Siastatin B microbial合成路线

Siastatin B microbial海关

[ 海关编码 ]: 2933399090

[ 中文概述 ]:
2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Siastatin B microbial文献

Contributions of NanI sialidase to Caco-2 cell adherence by Clostridium perfringens type A and C strains causing human intestinal disease.

Infect. Immun. 82(11) , 4620-30, (2014)

Previous studies showed that Clostridium perfringens type D animal disease strain CN3718 uses NanI sialidase for adhering to enterocyte-like Caco-2 cells. The current study analyzed whether NanI is si...

Syntheses and activities of N-substituted derivatives of siastatin B.

J. Antibiot. 45(10) , 1662-8, (1992)

N-Substituted derivatives of siastatin B have been obtained by a chemical modification. Some derivatives showed potent inhibitory activities against Streptococcus sp. and Clostridium perfringens neura...

Synthesis of 3-episiastatin B analogues having anti-influenza virus activity.

J. Antibiot. 46(12) , 1883-9, (1993)

Two epimers of siastatin B, 3-episiastatin B (3) and 3,4-diepisiastatin B (4), were obtained by the chemical modification of siastatin B. Compound 3 showed marked inhibitory activity against influenza...

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