茶碱-8-丁酸

茶碱-8-丁酸名称

[ CAS 号 ]:
5438-71-1

[ 中文名 ]:
茶碱-8-丁酸

[ 英文名 ]:
1H-Purine-8-butanoicacid, 2,3,6,9-tetrahydro-1,3-dimethyl-2,6-dioxo-

[英文别名 ]:

4-(1,3-dimethylxanth-8-yl)butyric acid
8-Theophyllinebutyric acid
8-carboxypropyltheophylline
8-(3-Carboxypropyl)-1,3-dimethylxanthine
8-(3-carboxypropyl)-theophylline
Theophylline-8-butyric acid

茶碱-8-丁酸物理化学性质

[ 密度 ]:
1.451g/cm3

[ 沸点 ]:
613.3ºC at 760mmHg

[ 分子式 ]:
C₁₁H₁₄N₄O₄

[ 分子量 ]:
266.25300

[ 闪点 ]:
324.7ºC

[ 精确质量 ]:
266.10200

[ PSA ]:
109.98000

[ 折射率 ]:
1.609

茶碱-8-丁酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XH5060000

CHEMICAL NAME :: Theophylline-8-butyric acid

CAS REGISTRY NUMBER :: 5438-71-1

LAST UPDATED :: 199712

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C11-H14-N4-O4

MOLECULAR WEIGHT :: 266.29

WISWESSER LINE NOTATION :: T56 BM DN FNVNVJ C3VQ F1 H1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#04358

茶碱-8-丁酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ RTECS号 ]:
XH5060000

[ 海关编码 ]:
2933990090

茶碱-8-丁酸合成路线

详细合成路线

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茶碱-8-丁酸海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

茶碱-8-丁酸文献

Theophylline radioimmunoassay: synthesis of antigen and characterization of antiserum.

Res. Commun. Chem. Pathol. Pharmacol. 13 , 497, (1976)

Antisera to theophylline (T) have been obtained by immunizing rabbits with a conjugate of 8-(3-carboxypropyl)-1,3-dimethylxanthine and bovine serum albumin. Comparison of 50% displacement values indic...

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