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氨基乙腈

氨基乙腈用途

噻吗心安的中间体。

氨基乙腈名称

[ CAS 号 ]:
540-61-4

[ 中文名 ]:
氨基乙腈

[ 英文名 ]:
Aminoacetonitrile

[中文别名 ]:

2-氨基乙腈

[英文别名 ]:

Aminoacetonitrile
ACETONITRILE,AMINO
Glycine Nitrile
EINECS 208-751-8
Glycinonitrile
Acetonitrile, 2-amino-
N-(cyanomethyl)-amine
Cyanomethylamine
Glycinenitrile
aminoacetonitrile hydrochloride

氨基乙腈物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
164.2±23.0 °C at 760 mmHg

[ 熔点 ]:
101°C (lit.)

[ 分子式 ]:
C₂H₄N₂

[ 分子量 ]:
56.067

[ 闪点 ]:
53.1±22.6 °C

[ 精确质量 ]:
56.037449

[ PSA ]:
49.81000

[ LogP ]:
-1.37

[ 外观性状 ]:
液体

[ 蒸汽压 ]:
2.0±0.3 mmHg at 25°C

[ 折射率 ]:
1.418

[ 储存条件 ]:
−20°C

氨基乙腈MSDS

详细MSDS(安全技术说明书)

氨基乙腈毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AL7750000

CHEMICAL NAME :: Acetonitrile, amino-

CAS REGISTRY NUMBER :: 540-61-4

BEILSTEIN REFERENCE NO. :: 0773694

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C2-H4-N2

MOLECULAR WEIGHT :: 56.08

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 300 mg/kg

SEX/DURATION :: female 15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - musculoskeletal system

REFERENCE :: VHAGAS Verhandlungen der Anatomischen Gesellschaft. (VEB Gustav Fischer Verlag, Postfach 176, Jena, DDR-6900, Ger. Dem. Rep.) V.1- 1887- Volume(issue)/page/year: 76,229,1982

氨基乙腈安全信息

[ 符号 ]:

GHS07, GHS08

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H312-H332-H351

[ 警示性声明 ]:
P280

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xn: Harmful;

[ 风险声明 (欧洲) ]:
R20/21/22;R40

[ 安全声明 (欧洲) ]:
23-36

[ 危险品运输编码 ]:
NA 1993 / PGIII

[ WGK德国 ]:
3

[ RTECS号 ]:
AL7750000

[ 海关编码 ]:
2926909090

氨基乙腈海关

[ 海关编码 ]: 2926909090

[ 中文概述 ]:
2926909090 其他腈基化合物. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

氨基乙腈文献

Monepantel irreversibly binds to and opens Haemonchus contortus MPTL-1 and Caenorhabditis elegans ACR-20 receptors.

Mol. Pharmacol. 87(1) , 96-102, (2015)

Monepantel is a recently developed anthelmintic with a novel mode of action. Parasitic nematodes with reduced sensitivity to monepantel have led to the identification of MPTL-1, a ligand-gated ion-cha...

Inhibition of ERK1/2 signaling prevents epileptiform behavior in rats prone to audiogenic seizures.

J. Neurochem. 132(2) , 218-29, (2015)

It has recently been proposed that extracellular signal-regulated kinases 1 and 2 (ERK1/2) are one of the factors mediating seizure development. We hypothesized that inhibition of ERK1/2 activity coul...

Haloperidol promotes mTORC1-dependent phosphorylation of ribosomal protein S6 via dopamine- and cAMP-regulated phosphoprotein of 32 kDa and inhibition of protein phosphatase-1.

Neuropharmacology 72 , 197-203, (2013)

The ribosomal protein S6 (rpS6) is a component of the small 40S ribosomal subunit, involved in multiple physiological functions. Here, we examined the effects produced by haloperidol, a typical antips...

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