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丝氨醇

丝氨醇用途

丝氨醇（2-氨基-1,3-丙二醇）是一种医药中间体，是用来合成碘帕醇（医药名称碘必乐）的主要原料。碘帕醇是一种非离子造影剂，作为血液系统、淋巴系统、泌尿系统、神经体统诊断试剂，现已在国外发达国家得到广泛应用。

丝氨醇名称

[ CAS 号 ]:
534-03-2

[ 中文名 ]:
2-氨基-1,3-丙二醇

[ 英文名 ]:
Serinol

[中文别名 ]:

[英文别名 ]:

2-amino-1,3-dihydroxypropane
2-Aminoglycerol
DL-Serinol
2-aMlno-1,3-propanedio
1,3-dihydroxy-2-aminopropane
2-amiopropan-1,3-diol
2-Aminopropan-1,3-diol
MFCD00051487
2-AMINO-1,3-PROPANDIOL
1,3-Propanediol, 2-amino-

丝氨醇物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
266.7±20.0 °C at 760 mmHg

[ 熔点 ]:
52-55 °C(lit.)

[ 分子式 ]:
C₃H₉NO₂

[ 分子量 ]:
91.109

[ 闪点 ]:
115.1±21.8 °C

[ 精确质量 ]:
91.063332

[ PSA ]:
66.48000

[ LogP ]:
-1.51

[ 外观性状 ]:
灰白色粘附性的结晶粉末

[ 蒸汽压 ]:
0.0±1.2 mmHg at 25°C

[ 折射率 ]:
1.496

[ 储存条件 ]:
存放于惰性气体之中;避免湿气 (吸湿)

[ 水溶解性 ]:
可溶于：甲醇

丝氨醇MSDS

详细MSDS(安全技术说明书)

丝氨醇安全信息

[ 符号 ]:

GHS05

[ 信号词 ]:
Danger

[ 危害声明 ]:
H314

[ 警示性声明 ]:
P280-P305 + P351 + P338-P310

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
C:Corrosive

[ 风险声明 (欧洲) ]:
R34

[ 安全声明 (欧洲) ]:
S26-S27-S28-S36/37/39-S45

[ 危险品运输编码 ]:
UN 3263 8/PG 2

[ WGK德国 ]:
1

[ 包装等级 ]:
III

[ 危险类别 ]:
8

[ 海关编码 ]:
2922199090

丝氨醇上下游产品

丝氨醇上游产品

丝氨醇下游产品

丝氨醇制备

用5-肟基-1,3-二噁烷经催化氢化，还原成5-氨基-1,3二噁烷，然后水解制得该品。

丝氨醇海关

[ 海关编码 ]: 2922199090

[ 中文概述 ]:
2922199090. 其他氨基醇及其醚，酯和它们的盐（但含一种以上含氧基的除外）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

丝氨醇文献

Novel Redox-Responsive Amphiphilic Copolymer Micelles for Drug Delivery: Synthesis and Characterization.

AAPS J. 17 , 1357-68, (2015)

A novel redox-responsive amphiphilic polymer was synthesized with bioreductive trimethyl-locked quinone propionic acid for a potential triggered drug delivery application. The aim of this study was to...

Design, synthesis and characterization of novel binary V(V)-Schiff base materials linked with insulin-mimetic vanadium-induced differentiation of 3T3-L1 fibroblasts to adipocytes. Structure-function correlations at the molecular level.

J. Inorg. Biochem. 147 , 99-115, (2015)

Among the various roles of vanadium in the regulation of intracellular signaling, energy metabolism and insulin mimesis, its exogenous activity stands as a contemporary challenge currently under inves...

Phospholipase D-catalyzed synthesis of new phospholipids with polar head groups.

Chem. Phys. Lipids 152(2) , 71-7, (2008)

A series of new phospholipids with polar head groups have been synthesized by enzymatic transphosphatidylation of 1,2-dioleoyl-sn-glycerophosphocholine and identified by 1H NMR and MALDI-TOF-MS. The a...

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丝氨醇