[R-(R,S)]-alpha-[1-(ethylmethylamino)ethyl]benzyl alcohol hydrochloride

名称

[ CAS 号 ]:
530-35-8

[ 英文名 ]:
[R-(R*,S*)]-alpha-[1-(ethylmethylamino)ethyl]benzyl alcohol hydrochloride

[英文别名 ]:

Nethamine hydrochloride
l-N-Ethylephedrine hydrochloride
Menetyl
Novedrin hydrochloride
EINECS 208-476-3

物理化学性质

[ 密度 ]:
0.995g/cm3

[ 沸点 ]:
294.8ºC at 760mmHg

[ 分子式 ]:
C₁₂H₁₉NO

[ 分子量 ]:
193.28500

[ 精确质量 ]:
193.14700

[ PSA ]:
23.47000

[ LogP ]:
2.06020

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DO5775000

CHEMICAL NAME :: Benzyl alcohol, alpha-(1-(ethylmethylamino)ethyl)-, hydrochloride, (-)-

CAS REGISTRY NUMBER :: 530-35-8

LAST UPDATED :: 199312

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C12-H19-N-O.Cl-H

MOLECULAR WEIGHT :: 229.78

WISWESSER LINE NOTATION :: QYR&Y1&N2&1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 60 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PHBUA9 Pharmaceutical Bulletin. (Tokyo, Japan) V.1-5, 1953-57. For publisher information, see CPBTAL. Volume(issue)/page/year: 3,465,1955

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 550 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Vascular - BP elevation not characterized in autonomic section Lungs, Thorax, or Respiration - respiratory stimulation

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 75,289,1942

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 70 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 39,382,1950

安全信息

[ 海关编码 ]:
2922199090

海关

[ 海关编码 ]: 2922199090

[ 中文概述 ]:
2922199090. 其他氨基醇及其醚，酯和它们的盐（但含一种以上含氧基的除外）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%