1,3-Dioxolane-4-methanaminium,N,N,N,2-tetramethyl-, iodide (1:1)

名称

[ CAS 号 ]:
4386-79-2

[ 英文名 ]:
1,3-Dioxolane-4-methanaminium,N,N,N,2-tetramethyl-, iodide (1:1)

[英文别名 ]:

F 2268
(+)-cis-dioxolane
Methamilane methiodide
Fourneau 2268

物理化学性质

[ 分子式 ]:
C₈H₁₈INO₂

[ 分子量 ]:
287.13800

[ 精确质量 ]:
287.03800

[ PSA ]:
18.46000

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BR7875000

CHEMICAL NAME :: Ammonium, ((2-methyl-1,3-dioxolan-4-yl)methyl)trimethyl-, iodide

CAS REGISTRY NUMBER :: 4386-79-2

LAST UPDATED :: 199112

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C8-H18-N-O2.I

MOLECULAR WEIGHT :: 287.17

WISWESSER LINE NOTATION :: T5O COTJ B1 D1K1&1&1 &Q &I

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 93,287,1948

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BSCIA3 Bulletin de la Societe de Chimie Biologique. (Paris, France) V.1-52, 1914-70. For publisher information, see BICMBE. Volume(issue)/page/year: 26,516,1944

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BSCIA3 Bulletin de la Societe de Chimie Biologique. (Paris, France) V.1-52, 1914-70. For publisher information, see BICMBE. Volume(issue)/page/year: 26,516,1944

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1200 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BSCIA3 Bulletin de la Societe de Chimie Biologique. (Paris, France) V.1-52, 1914-70. For publisher information, see BICMBE. Volume(issue)/page/year: 26,516,1944

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#01810

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 50 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948 Volume(issue)/page/year: -,410,1948

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 1 ug/kg

TOXIC EFFECTS :: Gastrointestinal - hypermotility, diarrhea Gastrointestinal - nausea or vomiting

REFERENCE :: BSCIA3 Bulletin de la Societe de Chimie Biologique. (Paris, France) V.1-52, 1914-70. For publisher information, see BICMBE. Volume(issue)/page/year: 26,516,1944

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 20 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BSCIA3 Bulletin de la Societe de Chimie Biologique. (Paris, France) V.1-52, 1914-70. For publisher information, see BICMBE. Volume(issue)/page/year: 26,516,1944

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 75 ug/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - other changes

REFERENCE :: BSCIA3 Bulletin de la Societe de Chimie Biologique. (Paris, France) V.1-52, 1914-70. For publisher information, see BICMBE. Volume(issue)/page/year: 26,516,1944

安全信息

[ 海关编码 ]:
2932999099

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海关

[ 海关编码 ]: 2932999099

[ 中文概述 ]:
2932999099. 其他仅含氧杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%