烯丙基雌烯醇
烯丙基雌烯醇用途
烯丙基雌烯醇名称
[ CAS 号 ]:
432-60-0
[ 中文名 ]:
烯丙基雌烯醇
[ 英文名 ]:
Allylestrenol
[中文别名 ]:
[英文别名 ]:
- allyloestrenol
- 17α-Allyl-4-oestrene-17β-ol
- EINECS 207-082-9
- organon
- allyl-estreno
- 17-Allylestr-4-en-17b-ol
- Estr-4-en-17β-ol, 17-allyl-
- Estr-4-en-17-ol, 17-(2-propen-1-yl)-, (17β)-
- 17α-Allylestr-4-en-17β-ol
- MFCD00198957
烯丙基雌烯醇生物活性
烯丙基雌烯醇物理化学性质
[ 密度 ]:
1.0±0.1 g/cm3
[ 沸点 ]:
405.4±44.0 °C at 760 mmHg
[ 熔点 ]:
78 - 81ºC
[ 分子式 ]:
C21H32O
[ 分子量 ]:
300.478
[ 闪点 ]:
170.6±20.7 °C
[ 精确质量 ]:
300.245331
[ PSA ]:
20.23000
[ LogP ]:
6.64
[ 外观性状 ]:
白色结晶粉末
[ 蒸汽压 ]:
0.0±2.1 mmHg at 25°C
[ 折射率 ]:
1.553
[ 储存条件 ]:
库房通风低温干燥,与食品原料分开存放
烯丙基雌烯醇毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KG7960000
- CHEMICAL NAME :
- Estr-4-en-17-beta-ol, 17-allyl-
- CAS REGISTRY NUMBER :
- 432-60-0
- BEILSTEIN REFERENCE NO. :
- 3148038
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C21-H32-O
- MOLECULAR WEIGHT :
- 300.53
- WISWESSER LINE NOTATION :
- L E5 B666 MUTJ E1 FQ F2U1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >640 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,41,1982 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 8 mg/kg
- SEX/DURATION :
- female 20 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - other measures of fertility
- REFERENCE :
- INJFA3 International Journal of Fertility. (Allen Press, 1041 New Hampshire, St., Lawrence, KS 66044) V.1- 1955- Volume(issue)/page/year: 9,57,1964
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 900 mg/kg
- SEX/DURATION :
- female 13-21 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - urogenital system
- REFERENCE :
- ACENA7 Acta Endocrinologica (Copenhagen). (Periodica, Skolegade 12 E, DK-2500 Valby, Denmark) V.1- 1948- Volume(issue)/page/year: 65,29,1970
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 300 mg/kg
- SEX/DURATION :
- male 15 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - testes, epididymis, sperm duct
- REFERENCE :
- IJMRAQ Indian Journal of Medical Research. (Indian Council of Medical Research, Ansari Nagar, New Delhi 110 029, India) V.1- 1913- Volume(issue)/page/year: 59,768,1971
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 15 mg/kg
- SEX/DURATION :
- male 15 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands
- REFERENCE :
- IJMRAQ Indian Journal of Medical Research. (Indian Council of Medical Research, Ansari Nagar, New Delhi 110 029, India) V.1- 1913- Volume(issue)/page/year: 59,768,1971
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 175 mg/kg
- SEX/DURATION :
- female 15-21 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - urogenital system
- REFERENCE :
- ACENA7 Acta Endocrinologica (Copenhagen). (Periodica, Skolegade 12 E, DK-2500 Valby, Denmark) V.1- 1948- Volume(issue)/page/year: 38,128,1961
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 900 mg/kg
- SEX/DURATION :
- female 13-21 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - urogenital system
- REFERENCE :
- ACENA7 Acta Endocrinologica (Copenhagen). (Periodica, Skolegade 12 E, DK-2500 Valby, Denmark) V.1- 1948- Volume(issue)/page/year: 65,29,1970
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intramuscular
- DOSE :
- 2100 ug/kg
- SEX/DURATION :
- female 15-19 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - behavioral
- REFERENCE :
- JDPHDH Journal of Developmental Physiology. (Oxford University Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1979- Volume(issue)/page/year: 19,67,1993
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intramuscular
- DOSE :
- 4500 ug/kg
- SEX/DURATION :
- female 15-19 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - biochemical and metabolic
- REFERENCE :
- GEPHDP General Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.6- 1975- Volume(issue)/page/year: 26,365,1995
烯丙基雌烯醇合成路线
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相关药品：
推荐生产厂家/供应商：
公司名：上海吉至生化科技有限公司
区域：上海市奉贤区
价格：
￥1268.0/1g
联系人：刘佳
产品详情：烯丙基雌烯醇
公司名：上海阿拉丁生化科技股份有限公司
区域：上海市浦东新区
价格：
￥449.9/1g
￥149.9/250mg
￥1799.9/5g
￥205.9/1ml
联系人：阿拉丁李高志
产品详情：烯丙基雌烯醇
公司名：上海创赛科技有限公司
区域：上海市嘉定区
价格：
￥380.0/250mg
￥1086.0/1g
联系人：夏言
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