三氟乙酸酐(TFAH)

三氟乙酸酐(TFAH)用途

【用途一】
用作分析试剂、溶剂、催化剂、脱水缩合剂与羟基和氨基三氟乙酰化时的保护剂
【用途二】
用作农药中间体
【用途三】
三氟乙酸酐是虫螨腈的中间体。
【用途四】
用作分析试剂、溶剂、催化剂、硝化反应促进剂、脱水缩合剂、羟基和氨基三氟乙酰化时的保护剂，有机合成。气相色谱分析中生物活性化合物。伯胺、仲胺的保护剂。也用于醛类氧化成酸类、酯类和胺类。

三氟乙酸酐(TFAH)名称

[ CAS 号 ]:
407-25-0

[ 中文名 ]:
三氟乙酸酐

[ 英文名 ]:
Trifluoroacetic anhydride

[中文别名 ]:

[英文别名 ]:

trifluoro acetic anhydride
trifluoroacetic
TRIFLUORACETIC ANHYDRIDE
Trifluoroacetyl anhydride
Perfluoracetic anhydride
trifluoroacetylanhydride
perfluoroaceticanhydride
MFCD00000416
Trifluoromethanesulfonic acid
2,2,2-trifluoroacetic anhydride

三氟乙酸酐(TFAH)物理化学性质

[ 密度 ]:
1.6±0.1 g/cm3

[ 沸点 ]:
39.5±0.0 °C at 760 mmHg

[ 熔点 ]:
-63.5 °C

[ 分子式 ]:
C₄F₆O₃

[ 分子量 ]:
210.031

[ 闪点 ]:
-26.1±20.8 °C

[ 精确质量 ]:
209.975159

[ PSA ]:
43.37000

[ LogP ]:
2.56

[ 外观性状 ]:
无色液体

[ 蒸汽压 ]:
438.6±0.0 mmHg at 25°C

[ 折射率 ]:
1.291

[ 储存条件 ]:
库房通风低温干燥,与H发孔剂、碱类、氰化物分开存放

[ 稳定性 ]:
Stable, but moisture sensitive. Reacts with water to liberate hydrogen (flammable!). Incompatible with water, strong oxidizing agents.

[ 水溶解性 ]:
Hydrolysis

三氟乙酸酐(TFAH)MSDS

三氟乙酸酐(TFAH)毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AJ9800000

CHEMICAL NAME :: Acetic acid, trifluoro-, anhydride

CAS REGISTRY NUMBER :: 407-25-0

BEILSTEIN REFERENCE NO. :: 0746197

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C4-F6-O3

MOLECULAR WEIGHT :: 210.04

WISWESSER LINE NOTATION :: FXFFVOVXFFF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,575,1986

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,575,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4633 No. of Facilities: 147 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 5451 (estimated) No. of Female Employees: 1249 (estimated)

三氟乙酸酐(TFAH)安全信息

[ 符号 ]:

GHS05, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H314-H332

[ 补充危害声明 ]:
Reacts violently with water.

[ 警示性声明 ]:
P280-P305 + P351 + P338-P310

[ 个人防护装备 ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US)

[ 危害码 (欧洲) ]:
C:Corrosive

[ 风险声明 (欧洲) ]:
R14;R20;R35;R52/53

[ 安全声明 (欧洲) ]:
S26-S36/37/39-S43-S45-S61-S9-S8-S28A-S27

[ 危险品运输编码 ]:
UN 3265 8/PG 1

[ WGK德国 ]:
2

[ RTECS号 ]:
AJ9800000

[ 包装等级 ]:
I

[ 危险类别 ]:
8

[ 海关编码 ]:
29159080

三氟乙酸酐(TFAH)合成路线

三氟乙酸酐(TFAH)上下游产品

三氟乙酸酐(TFAH)上游产品

三氟乙酸酐(TFAH)下游产品

三氟乙酸酐(TFAH)制备

其制备方法是用三氟乙酸与二氯乙酸酐反应。反应方程式：CF₃COOH+(Cl₂CHCO)₂O→(CF₃CO)₂O+Cl₂CHCOOH

三氟乙酸酐(TFAH)海关

[ 海关编码 ]: 2915900090

[ 中文概述 ]:
2915900090. 其他饱和无环一元羧酸及其酸酐（酰卤、过氧）化物、过氧酸及其卤化、硝化、磺化、亚硝化衍生物. 增值税率:17.0%. 退税率:9.0%. 监管条件:AB(入境货物通关单,出境货物通关单). 最惠国关税:5.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验

[ Summary ]:
2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

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