左芬氟拉明

左芬氟拉明名称

[ CAS 号 ]:
37577-24-5

[ 中文名 ]:
左芬氟拉明

[ 英文名 ]:
(R)-fenfluramine

[英文别名 ]:

Levofenfluramina
Fenfluramine l-form
Levofenfluraminum
Levofenfluramine
l-Fenfluramine
dextrofenfluramine
dexfenfluramine

左芬氟拉明物理化学性质

[ 密度 ]:
1.078g/cm3

[ 沸点 ]:
243.1ºC at 760mmHg

[ 分子式 ]:
C₁₂H₁₇ClF₃N

[ 分子量 ]:
267.71800

[ 闪点 ]:
100.8ºC

[ 精确质量 ]:
267.10000

[ PSA ]:
12.03000

[ LogP ]:
4.43880

[ 折射率 ]:
1.455

左芬氟拉明毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SH6824000

CHEMICAL NAME :: Phenethylamine, N-ethyl-alpha-methyl-m-trifluoromethyl-, l-

CAS REGISTRY NUMBER :: 37577-24-5

LAST UPDATED :: 198910

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C12-H16-F3-N

MOLECULAR WEIGHT :: 231.29

WISWESSER LINE NOTATION :: FXFFR CY1&1M2 -L

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 195 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 161,206,1966

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 77 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 161,206,1966

左芬氟拉明安全信息

[ 符号 ]:

GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H301 + H311 + H331

[ 警示性声明 ]:
Missing Phrase - N15.00950417-P261-P280-P302 + P352 + P312-P304 + P340 + P312-P403 + P233

[ 个人防护装备 ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
T: Toxic;

[ 风险声明 (欧洲) ]:
23/24/25

[ 安全声明 (欧洲) ]:
22-26-36

[ 危险品运输编码 ]:
UN 2811 6.1/PG 3

[ RTECS号 ]:
SH6824000

[ 海关编码 ]:
2921499090

左芬氟拉明海关

[ 海关编码 ]: 2921499090

[ 中文概述 ]:
2921499090 其他芳香单胺及衍生物及它们的盐. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

左芬氟拉明文献

[Phentermine--a "weighty" or a dangerous substance?].

Arch. Kriminol. 231(3-4) , 116-29, (2013)

According to international surveys, the appetite suppressant phentermine has frequently been seized although its approval has been withdrawn in Germany. Phentermine is an isomer of methamphetamine tho...

Rapid screening of illicit additives in weight loss dietary supplements with desorption corona beam ionisation (DCBI) mass spectrometry.

Food Addit. Contam. Part A. Chem. Anal. Control. Expo. Risk Assess. 29(8) , 1194-201, (2012)

Desorption corona beam ionisation (DCBI), the relatively novel ambient mass spectrometry (MS) technique, was utilised to screen for illicit additives in weight-loss food. The five usually abused chemi...

Biphasic mechanisms of amphetamine action at the dopamine terminal.

J. Neurosci. 34(16) , 5575-82, (2014)

In light of recent studies suggesting that amphetamine (AMPH) increases electrically evoked dopamine release ([DA]o), we examined discrepancies between these findings and literature that has demonstra...

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