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D-组氨酸

D-组氨酸用途

D-Histidine 是 L-histidine (HY-N0832) 的对映体。 L-histidine 是婴儿必需的氨基酸。L-histidine 是线粒体谷氨酰胺转运的抑制剂。

D-组氨酸名称

[ CAS 号 ]:
351-50-8

[ 中文名 ]:
D-组氨酸

[ 英文名 ]:
H-D-His-OH

[中文别名 ]:

[英文别名 ]:

D-Histidine
(R)-2-Amino-3-(1H-imidazol-4-yl)propanoic acid
H-D-His-OH
Histidine
EINECS 206-513-8
hydrogen D-histidinate
MFCD00065963
D-His-OH
(2R)-2-amino-3-(1H-imidazol-5-yl)propanoic acid

D-组氨酸生物活性

[ 描述 ]:

D-Histidine 是 L-histidine (HY-N0832) 的对映体。 L-histidine 是婴儿必需的氨基酸。L-histidine 是线粒体谷氨酰胺转运的抑制剂。

[ 相关类别 ]:

研究领域 >> 代谢疾病

[ 靶点 ]

Human Endogenous Metabolite

[参考文献]

[1]. Bou Zeidan M, et al. L-histidine inhibits biofilm formation and FLO11-associated phenotypes in Saccharomyces cerevisiae flor yeasts. PLoS One. 2014 Nov 4;9(11):e112141.

D-组氨酸物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
458.9±35.0 °C at 760 mmHg

[ 熔点 ]:
287ºC

[ 分子式 ]:
C₆H₉N₃O₂

[ 分子量 ]:
155.155

[ 闪点 ]:
231.3±25.9 °C

[ 精确质量 ]:
155.069473

[ PSA ]:
92.00000

[ LogP ]:
-1.26

[ 外观性状 ]:
白色结晶粉末

[ 蒸汽压 ]:
0.0±1.2 mmHg at 25°C

[ 折射率 ]:
1.615

[ 储存条件 ]:
室温

D-组氨酸MSDS

详细MSDS(安全技术说明书)

D-组氨酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xn

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2933290090

D-组氨酸上下游产品

D-组氨酸上游产品

D-组氨酸下游产品

D-组氨酸海关

[ 海关编码 ]: 2933290090

[ 中文概述 ]:
2933290090. 其他结构含非稠合咪唑环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

D-组氨酸文献

Carbonic anhydrase activators: activation of the human tumor-associated isozymes IX and XII with amino acids and amines.

Bioorg. Med. Chem. 16 , 3530-6, (2008)

The first activation study of the human carbonic anhydrase (hCA, EC 4.2.1.1) isoforms associated to tumors, hCA IX and XII, with a small library of natural and non-natural amino acids as well as aroma...

Carbonic anhydrase activators: activation of isozyme XIII with amino acids and amines.

Bioorg. Med. Chem. Lett. 16 , 3955-9, (2006)

The first activation study of isoform XIII of carbonic anhydrase (CA, EC 4.2.1.1) is reported. A series of amino acids and amines incorporating protonatable moieties of the primary/heterocyclic amine ...

Carbonic anhydrase activators: the first activation study of the human secretory isoform VI with amino acids and amines.

Bioorg. Med. Chem. 15 , 5351-7, (2007)

The secretory isozyme of human carbonic anhydrase (hCA, EC 4.2.1.1), hCA VI, has been cloned, expressed, and purified in a bacterial expression system. The kinetic parameters for the CO(2) hydration r...

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