4-甲氧甲基苄基菊酸酯

4-甲氧甲基苄基菊酸酯用途

【用途一】
属卫生杀虫剂，对蚊蝇等卫生害虫驱避性好，杀死能力强
【用途二】
拟除虫菊酯类杀虫剂。具有沸点低、蒸气压高的特点，用于防治卫生害虫，可作为加工蚊香用，也是制造电热驱蚊片的主要原料。也可用1%甲醚菊酯煤油制剂，每立方米空间含药剂10mL时，蚊子在8min内全部击倒，24h内死亡率达100%。
【用途三】
主要用于防治蚊蝇等害虫，常用来制作蚊香及电热驱蚊片，具有击倒速度快、驱避性能好、杀伤力强等特点。用于蚊香中一般含有效成分为0.35%，也可配制喷雾剂、气雾剂、熏蒸剂等。

4-甲氧甲基苄基菊酸酯名称

[ CAS 号 ]:
34388-29-9

[ 中文名 ]:
甲醚菊酯

[ 英文名 ]:
methothrin

[中文别名 ]:

[英文别名 ]:

methothryn
CHRYSANTHEMUMMONOCARBOXYLATE
yl)benzylester
4-(methoxymethyl)benzyl (1RS,3RS
mbpyrethroid
METHOTHRIN
enzylester

4-甲氧甲基苄基菊酸酯物理化学性质

[ 密度 ]:
1.075 g/cm3

[ 沸点 ]:
369.639ºC at 760 mmHg

[ 分子式 ]:
C₁₉H₂₆O₃

[ 分子量 ]:
302.40800

[ 闪点 ]:
154.79ºC

[ 精确质量 ]:
302.18800

[ PSA ]:
35.53000

[ LogP ]:
4.11460

[ 折射率 ]:
1.501

4-甲氧甲基苄基菊酸酯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GZ1800000

CHEMICAL NAME :: Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methylpropenyl)-, p-(methoxymethyl) benzyl ester

CAS REGISTRY NUMBER :: 34388-29-9

LAST UPDATED :: 198806

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C19-H26-O3

MOLECULAR WEIGHT :: 302.45

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: CHYCDW Zhonghua Yufangyixue Zazhi. Chinese Journal of Preventive Medicine. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) Beginning history not known. Volume(issue)/page/year: 17,8,1983 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 900 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CHYCDW Zhonghua Yufangyixue Zazhi. Chinese Journal of Preventive Medicine. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) Beginning history not known. Volume(issue)/page/year: 17,8,1983

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1747 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CHYCDW Zhonghua Yufangyixue Zazhi. Chinese Journal of Preventive Medicine. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) Beginning history not known. Volume(issue)/page/year: 17,8,1983

4-甲氧甲基苄基菊酸酯安全信息

[ 危害码 (欧洲) ]:
T

[ 风险声明 (欧洲) ]:
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . R36/37/38:Irritating to eyes, respiratory system and skin .

[ 安全声明 (欧洲) ]:
S22-S36

[ 危险品运输编码 ]:
3439

4-甲氧甲基苄基菊酸酯制备

1 .菊酸的制备以丙酮和乙炔为基本原料，合成2,5-二甲基-2，4-己二烯，再在铜催化剂下与重氮乙酸酯成环，生成菊酸。

2. 4-（甲氧甲基）苄氯的制备以对二甲苯为原料，经侧链氯化后制得对氯甲基苄氯，经醚化反应制得。

3. 甲醚菊酯的合成由菊酸钠与4-（甲氧甲基）苄氯在溶剂中反应制得。操作过程是：将10g菊酸乙酯，用氢氧化钠乙醇溶液皂化，脱去乙醇、水后，加极性非质子溶剂10mL、4-（甲氧甲基）苄氯9g、催化剂0.1g，于85～90℃反应2h。冷却，滤去氯化钠，减压蒸馏，得产品12.3g (82%)，