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半胱氨酸

半胱氨酸用途

2-氨基-3-巯基丙酸是一种半胱氨酸衍生物[1]。

半胱氨酸名称

[ CAS 号 ]:
3374-22-9

[ 中文名 ]:
DL-半胱氨酸

[ 英文名 ]:
DL-CYSTEINE (1-13C)

[中文别名 ]:

[英文别名 ]:

dl-2-amino-3-mercaptopropionic acid
MFCD00004881
Cysteine
2-Amino-3-mercaptopropanoic acid
DL-Cysteine
2-amino-3-sulfopropionic acid
hydrogen cysteinate
CYSTEINE, DL-
2-amino-3-sulfanylpropanoic acid
2-Amino-3-mercaptopropionic acid

半胱氨酸生物活性

[ 描述 ]:

2-氨基-3-巯基丙酸是一种半胱氨酸衍生物[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[体外研究]

氨基酸和氨基酸衍生物已被商业化用作能量补充剂。它们影响合成代谢激素的分泌、运动期间的燃料供应、压力相关任务期间的精神表现,并防止运动引起的肌肉损伤。它们被认为是有益的能生膳食物质[1]。

[参考文献]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807.

半胱氨酸物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
293.9±35.0 °C at 760 mmHg

[ 熔点 ]:
225ºC (dec.)

[ 分子式 ]:
C₃H₇NO₂S

[ 分子量 ]:
121.158

[ 闪点 ]:
131.5±25.9 °C

[ 精确质量 ]:
121.019745

[ PSA ]:
102.12000

[ LogP ]:
0.23

[ 外观性状 ]:
白色固体

[ 蒸汽压 ]:
0.0±1.3 mmHg at 25°C

[ 折射率 ]:
1.550

[ 储存条件 ]:
室温，避光

[ 稳定性 ]:
Stable. Incompatible with strong oxidizing agents,

半胱氨酸MSDS

详细MSDS(安全技术说明书)

半胱氨酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HA1595000

CHEMICAL NAME :: Cysteine, DL-

CAS REGISTRY NUMBER :: 3374-22-9

LAST UPDATED :: 199712

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C3-H7-N-O2-S

MOLECULAR WEIGHT :: 121.17

WISWESSER LINE NOTATION :: QVYZ1SH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1250 mg/kg/2D-I

TOXIC EFFECTS :: Liver - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases

MUTATION DATA

TYPE OF TEST :: Phage inhibition capacity

TEST SYSTEM :: Bacteria - Escherichia coli

DOSE/DURATION :: 5 mg/L

REFERENCE :: APMBAY Applied Microbiology. (Washington, DC) V.1-30, 1953-75. For publisher information, see AEMIDF. Volume(issue)/page/year: 12,234,1964

半胱氨酸安全信息

[ 符号 ]:

GHS05, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H302-H314-H335

[ 警示性声明 ]:
P280-P301 + P312 + P330-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn,Xi

[ 风险声明 (欧洲) ]:
R20/21/22

[ 安全声明 (欧洲) ]:
26-36/37/39

[ 危险品运输编码 ]:
UN 2923 6.1(8) / PGIII

[ WGK德国 ]:
3

[ RTECS号 ]:
HA1595000

[ 海关编码 ]:
2930909090

半胱氨酸制备

【方法一】
以DL-半胱氨酸盐酸盐为原料，用碱中和后过滤、干燥，精制而得。

半胱氨酸海关

[ 海关编码 ]: 2930909090

[ 中文概述 ]:
2930909090. 其他有机硫化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

半胱氨酸文献

A survey of the interactome of Kaposi's sarcoma-associated herpesvirus ORF45 revealed its binding to viral ORF33 and cellular USP7, resulting in stabilization of ORF33 that is required for production of progeny viruses.

J. Virol. 89(9) , 4918-31, (2015)

The ORF45 protein of Kaposi's sarcoma-associated herpesvirus (KSHV) is a gammaherpesvirus-specific immediate-early tegument protein. Our previous studies have revealed its crucial roles in both early ...

Insight into PreImplantation Factor (PIF*) mechanism for embryo protection and development: target oxidative stress and protein misfolding (PDI and HSP) through essential RIKP [corrected] binding site.

PLoS ONE 9(7) , e100263, (2014)

Endogenous PIF, upon which embryo development is dependent, is secreted only by viable mammalian embryos, and absent in non-viable ones. Synthetic PIF (sPIF) administration promotes singly cultured em...

Hepatitis E virus (HEV) protease: a chymotrypsin-like enzyme that processes both non-structural (pORF1) and capsid (pORF2) protein.

J. Gen. Virol. 95(Pt 8) , 1689-700, (2014)

Hepatitis E virus (HEV), a major cause of acute viral hepatitis across the world, is a non-enveloped, plus-strand RNA virus. Its genome codes three proteins, pORF1 (multifunctional polyprotein), pORF2...

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