全氟辛酸

全氟辛酸用途

【用途一】
用作CTFE、TFE及氟橡胶聚合分散剂
【用途二】
主要用作表面活性剂、乳化剂、全氟辛酸及其钠盐或铵盐用于四氟乙烯聚合及氟橡胶生产时作分散剂，也用作制备增水、憎油剂的原料和选矿剂。
【用途三】
被用作高效表面活性剂、分散剂、添加剂等。全氟辛酸及其衍生物作为重要的有机中间体可用于合成含氟憎水憎油剂、皮革整理剂等产品。

全氟辛酸名称

[ CAS 号 ]:
335-67-1

[ 中文名 ]:
全氟辛酸

[ 英文名 ]:
Perfluorooctanoic Acid

[中文别名 ]:

[英文别名 ]:

A 5717
[14C]-Perfluorooctanoic acid
nPFOA
Eftop EF 201
perfluorocaprylic acid
RARECHEM AL BO 0424
pentadecafluorocaprylic acid
Pentadecafluorooctanoic acid
octanoic acid, pentadecafluoro-
EF 201

全氟辛酸物理化学性质

[ 密度 ]:
1.7±0.1 g/cm3

[ 沸点 ]:
188.0±0.0 °C at 760 mmHg

[ 熔点 ]:
55-56 °C(lit.)

[ 分子式 ]:
C₈HF₁₅O₂

[ 分子量 ]:
414.068

[ 闪点 ]:
62.1±25.9 °C

[ 精确质量 ]:
413.973694

[ PSA ]:
37.30000

[ LogP ]:
7.75

[ 外观性状 ]:
白色或灰白色粉末

[ 蒸汽压 ]:
0.3±0.7 mmHg at 25°C

[ 折射率 ]:
1.289

[ 储存条件 ]:
2-8°C

[ 稳定性 ]:
Stable. Incompatible with bases, oxidizing agents, reducing agents.

[ 水溶解性 ]:
3.4 g/L

全氟辛酸MSDS

详细MSDS(安全技术说明书)

全氟辛酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RH0781000

CHEMICAL NAME :: Octanoic acid, pentadecafluoro-

CAS REGISTRY NUMBER :: 335-67-1

BEILSTEIN REFERENCE NO. :: 1809678

LAST UPDATED :: 199710

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C8-H-F15-O2

MOLECULAR WEIGHT :: 414.09

WISWESSER LINE NOTATION :: QVXFFXFFXFFXFFXFFXFFXFFF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 189 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 42 mg/kg/7D-I

TOXIC EFFECTS :: Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other transferases Biochemical - Metabolism (Intermediary) - lipids including transport

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 84 mg/kg/2W-C

TOXIC EFFECTS :: Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other oxidoreductases

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1092 mg/kg/26W-C

TOXIC EFFECTS :: Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other oxidoreductases

TYPE OF TEST :: DNA damage

MUTATION DATA

TEST SYSTEM :: Rodent - rat

DOSE/DURATION :: 168 mg/kg/2W (Continuous)

REFERENCE :: CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 57,55,1991

全氟辛酸安全信息

[ 符号 ]:

GHS05, GHS07, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H302 + H332-H318-H351-H360D-H362-H372

[ 警示性声明 ]:
P201-P260-P263-P280-P305 + P351 + P338 + P310-P308 + P313

[ 靶器官 ]:
Liver

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
C:Corrosive

[ 风险声明 (欧洲) ]:
R34

[ 安全声明 (欧洲) ]:
S26-S36/37/39-S45-S36/37

[ 危险品运输编码 ]:
UN 3261 8/PG 3

[ WGK德国 ]:
2

[ RTECS号 ]:
RH0781000

[ 包装等级 ]:
III

[ 危险类别 ]:
8

[ 海关编码 ]:
29159080

全氟辛酸上下游产品

全氟辛酸上游产品

全氟辛酸下游产品

全氟辛酸制备

在由镍阳极和铁阴极交替组成的电极组的电解槽内，加入无水液体氟化氢、辛酰氯和少量的正丁基硫醇，混合均匀后，通入2500A的直流电。在电解过程中为维持电解液的浓度，需不断补加辛酰氯。电解产物不溶于电解液而沉于电解槽底，需隔一定时间放出。电解液温度控制在24℃。电压控制在5～8V之间进行电解操作。电解过程中产生的气体，经冷凝器冷却冷凝至-30℃以下，再经缓冲器及水加压，使系统保持在0.042MPa的压力，然后将气体放空。电解产物经氢氧化钠中和、硫酸酸化，再送精馏塔精馏，收集1.33kPa，91.5～93.5℃的馏分即为成品。

电解：

酯化：

2.将原料辛酰氯（纯度99.5%）与氟化氢及少量正丁基硫酸投入电解槽，于20~25℃下通电（电压5～8），电解产物用碱中和，再用酸酸化，蒸馏之，即得全氟辛酸。

全氟辛酸海关

[ 海关编码 ]: 2915900090

[ 中文概述 ]:
2915900090. 其他饱和无环一元羧酸及其酸酐（酰卤、过氧）化物、过氧酸及其卤化、硝化、磺化、亚硝化衍生物. 增值税率:17.0%. 退税率:9.0%. 监管条件:AB(入境货物通关单,出境货物通关单). 最惠国关税:5.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验

[ Summary ]:
2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

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