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聚乙二醇单-4-壬苯醚n≈5

聚乙二醇单-4-壬苯醚n≈5用途

4-Nonylphenol polyethoxylate是一表面活性剂,常用于避孕药中作为杀精剂。

聚乙二醇单-4-壬苯醚n≈5名称

[ CAS 号 ]:
26027-38-3

[ 中文名 ]:
壬基酚聚氧乙烯醚

[ 英文名 ]:
4-Nonylphenol polyethoxylate

[中文别名 ]:

[英文别名 ]:

nonoxynol-4
NONOXINOLS
nonoxynol-2
Polyethylene Glycol Mono-4-nonylphenyl Ether n≈7.5
tergitol R(NP 10)
Conceptol
Novoxynol
MFCD00134080
Tergitol7
n-9

聚乙二醇单-4-壬苯醚n≈5生物活性

[ 描述 ]:

4-Nonylphenol polyethoxylate是一表面活性剂,常用于避孕药中作为杀精剂。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 其他

[相关活性小分子]

聚乙二醇单-4-壬苯醚n≈5物理化学性质

[ 密度 ]:
1.06

[ 沸点 ]:
250ºC

[ 熔点 ]:
57-58ºC

[ 分子式 ]:
C₂₈H₅₀O₈

[ 分子量 ]:
514.69200

[ 闪点 ]:
94ºC

[ 精确质量 ]:
514.35100

[ PSA ]:
84.84000

[ LogP ]:
3.87110

[ 外观性状 ]:
透明油性液体

[ 折射率 ]:
1.4950-1.4990

[ 储存条件 ]:
0-6°C

[ 水溶解性 ]:
Miscible with water, with ethanol (96 per cent) and with vegetable oils.

聚乙二醇单-4-壬苯醚n≈5MSDS

详细MSDS(安全技术说明书)

聚乙二醇单-4-壬苯醚n≈5毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MD0906000

CHEMICAL NAME :: Glycols, polyethylene, mono(p-nonylphenyl) ether

CAS REGISTRY NUMBER :: 26027-38-3

LAST UPDATED :: 199710

DATA ITEMS CITED :: 15

WISWESSER LINE NOTATION :: /*O2*/ *9R D **Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2860 mg/kg/22D-I

TOXIC EFFECTS :: Liver - changes in liver weight Endocrine - changes in spleen weight Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intrauterine

DOSE :: 2500 ug/kg

SEX/DURATION :: female 1 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intrauterine

DOSE :: 5 mg/kg

SEX/DURATION :: female 1 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Fertility - other measures of fertility

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravaginal

DOSE :: 50 mg/kg

SEX/DURATION :: female 1 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Maternal Effects - uterus, cervix, vagina Reproductive - Maternal Effects - other effects

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravaginal

DOSE :: 50 mg/kg

SEX/DURATION :: female 3 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravaginal

DOSE :: 1250 ug/kg

SEX/DURATION :: female 10 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Maternal Effects - uterus, cervix, vagina

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravaginal

DOSE :: 1 mg/kg

SEX/DURATION :: female 1 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)

MUTATION DATA

TYPE OF TEST :: Morphological transformation

TEST SYSTEM :: Rodent - mouse Fibroblast

DOSE/DURATION :: 10 ppm

REFERENCE :: CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 3,553,1982 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M4862 No. of Facilities: 82021 (estimated) No. of Industries: 303 No. of Occupations: 188 No. of Employees: 842001 (estimated) NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T0292 No. of Facilities: 3063 (estimated) No. of Industries: 12 No. of Occupations: 20 No. of Employees: 9425 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X8533 No. of Facilities: 30457 (estimated) No. of Industries: 190 No. of Occupations: 159 No. of Employees: 1297228 (estimated) No. of Female Employees: 863213 (estimated)

聚乙二醇单-4-壬苯醚n≈5安全信息

[ 符号 ]:

GHS05, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H302-H318-H412

[ 警示性声明 ]:
P280-P301 + P312 + P330-P305 + P351 + P338 + P310

[ 危险品运输编码 ]:
NONH for all modes of transport

[ RTECS号 ]:
MD0906000