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亚氨基芪

亚氨基芪用途

Iminostilbene 是 carbamazepine 的化学前体。

亚氨基芪名称

[ CAS 号 ]:
256-96-2

[ 中文名 ]:
亚氨基芪

[ 英文名 ]:
Iminostilbene

[中文别名 ]:

[英文别名 ]:

dibenz[b,f]azepine
MFCD00799229
Minostilbene
EINECS 249-478-4
5H-Dibenz[b,f]azepine
2,2'-Iminostilbense
Iminostilbene
Iminostilben
R-FMOC
5H-Dibenzo[b,f]azepine

亚氨基芪生物活性

[ 描述 ]:

Iminostilbene 是 carbamazepine 的化学前体。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Christian P, et al. Crystallization of Carbamazepine in Proximity to Its Precursor Iminostilbene and a Silica Surface. Cryst Growth Des. 2016 May 4;16(5):2771-2778. Epub 2016 Mar 30.

亚氨基芪物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
349.1±22.0 °C at 760 mmHg

[ 熔点 ]:
197 °C

[ 分子式 ]:
C₁₄H₁₁N

[ 分子量 ]:
193.244

[ 闪点 ]:
178.4±17.8 °C

[ 精确质量 ]:
193.089142

[ PSA ]:
12.03000

[ LogP ]:
4.11

[ 外观性状 ]:
黄色至棕色粉末

[ 蒸汽压 ]:
0.0±0.8 mmHg at 25°C

[ 折射率 ]:
1.627

[ 储存条件 ]:
Refrigerator

[ 水溶解性 ]:
dioxane: 50 mg/mL, clear

亚氨基芪MSDS

详细MSDS(安全技术说明书)

亚氨基芪安全信息

[ 符号 ]:

GHS07, GHS09

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H411

[ 警示性声明 ]:
P273

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn:Harmful

[ 风险声明 (欧洲) ]:
R22;R51/53

[ 安全声明 (欧洲) ]:
S26-S36/37/39-S45-S61

[ 危险品运输编码 ]:
UN 3265 8/PG 2

[ WGK德国 ]:
3

[ 海关编码 ]:
2933990090

亚氨基芪上下游产品

亚氨基芪上游产品

亚氨基芪下游产品

亚氨基芪制备

【方法一】
由10.11二氢-5H-二苯骈[b,f]氮杂[494-19-9]经消除而得。

亚氨基芪海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

亚氨基芪文献

Free-radical-scavenging effect of carbazole derivatives on AAPH-induced hemolysis of human erythrocytes.

Bioorg. Med. Chem. 15 , 1903-13, (2007)

Since the research on antioxidants provides theoretical information for the medicinal development, and supplies some in vitro methods for quick-optimizing drugs, it attracts more scientific attention ...

Simulation of the hepatic metabolism of stilbene and its tricyclic derivatives by Fenton and Ruff reagents: models for cytochrome P-450 activation of chemical carcinogens.

Biopharm. Drug Dispos. 11(1) , 39-51, (1990)

Reactions of trans-stilbene, cis-stilbene, 5H-dibenzo [a,d] cyclo-heptene 5-one and 5H-dibenz [b,f] azepine (iminostilbene) with Fenton reagent [Fe (II)/H2O2] clearly simulate their hepatic metabolism...

Synthesis and antioxidant properties of some novel 5H-dibenz[b,f]azepine derivatives in different in vitro model systems.

Eur. J. Med. Chem. 45 , 2-10, (2010)

A series of 5H-dibenz[b,f]azepine containing different aminophenols and substituted aminophenols were synthesized. 3-chloro-1-(5H-dibenz[b,f]azepine-5yl)propan-1-one (2) was obtained by N-acylation of...

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