双(3,4-二氯苯基)二氮烯-1-氧化物

双(3,4-二氯苯基)二氮烯-1-氧化物名称

[ CAS 号 ]:
21232-47-3

[ 中文名 ]:
双(3,4-二氯苯基)二氮烯-1-氧化物

[ 英文名 ]:
3,3',4,4'-TETRACHLOROAZOXYBENZENE

[中文别名 ]:

[英文别名 ]:

双(3,4-二氯苯基)二氮烯-1-氧化物物理化学性质

[ 密度 ]:
1.53g/cm3

[ 沸点 ]:
472.7ºC at 760 mmHg

[ 分子式 ]:
C12H6Cl4N2O

[ 分子量 ]:
336.00100

[ 闪点 ]:
239.7ºC

[ 精确质量 ]:
333.92300

[ PSA ]:
41.11000

[ LogP ]:
6.74910

[ 蒸汽压 ]:
1.19E-08mmHg at 25°C

[ 折射率 ]:
1.641

双(3,4-二氯苯基)二氮烯-1-氧化物毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CO4150000
CHEMICAL NAME :
Azoxybenzene, 3,3',4,4'-tetrachloro-
CAS REGISTRY NUMBER :
21232-47-3
LAST UPDATED :
199712
DATA ITEMS CITED :
11
MOLECULAR FORMULA :
C12-H6-Cl4-N2-O
MOLECULAR WEIGHT :
336.00

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
80 mg/kg/17W-C
TOXIC EFFECTS :
Liver - changes in liver weight Blood - changes in erythrocyte (RBC) count Related to Chronic Data - changes in testicular weight
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
650 mg/kg/13W-I
TOXIC EFFECTS :
Behavioral - food intake (animal) Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
350 mg/kg/48D-I
TOXIC EFFECTS :
Liver - other changes Endocrine - changes in thymus weight Related to Chronic Data - changes in testicular weight
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
200 mg/kg/28D-I
TOXIC EFFECTS :
Liver - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
75600 ug/kg
SEX/DURATION :
female 14 day(s) pre-mating - 28 day(s) post-birth
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - blood and lymphatic systems (including spleen and marrow) Reproductive - Effects on Newborn - live birth index (measured after birth)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
7560 ug/kg
SEX/DURATION :
female 14 day(s) pre-mating - 28 day(s) post-birth
TOXIC EFFECTS :
Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
16 mg/kg
SEX/DURATION :
female 12 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetal death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
6 mg/kg
SEX/DURATION :
female 11 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - urogenital system

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
134 mg/kg/4W (Continuous)
REFERENCE :
AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- Volume(issue)/page/year: 14,677,1985

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