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毛蕊异黄酮

毛蕊异黄酮用途

毛蕊异黄酮 (Calycosin)是一抗氧化和抗炎症活性天然化合物。

毛蕊异黄酮名称

[ CAS 号 ]:
20575-57-9

[ 中文名 ]:
毛蕊异黄酮

[ 英文名 ]:
Calycosin

[中文别名 ]:

[英文别名 ]:

7,5'-dihydroxy-4'-methoxyisoflavone
7,3'-dihydroxy-4'-methoxyisoflavone
3'-hydroxyformononetin
3',7-Dihydroxy-4'-methoxy-isoflavone
Calycosin
3',7-dihydroxy-4'-methoxyisoflavone
7,3'-dihydroxy-4'-methoxyisoflavanon-2-ene

毛蕊异黄酮生物活性

[ 描述 ]:

毛蕊异黄酮 (Calycosin)是一抗氧化和抗炎症活性天然化合物。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 癌症

天然产物 >> 黄酮类化合物

[参考文献]

[1]. Zhou Y, et al. Calycosin induces apoptosis in human ovarian cancer SKOV3 cells by activating caspases and Bcl-2 family proteins. Tumour Biol. 2015 Feb 12.

[2]. Chen J, et al. Calycosin and genistein induce apoptosis by inactivation of HOTAIR/p-Akt signaling pathway in human breast cancer MCF-7 cells. Cell Physiol Biochem. 2015;35(2):722-8.

[3]. Chen J, et al. Calycosin suppresses breast cancer cell growth via ERβ-dependent regulation of IGF-1R, p38 MAPK and PI3K/Akt pathways. PLoS One. 2014 Mar 11;9(3):e91245.

[4]. Chen J, et al. Calycosin promotes proliferation of estrogen receptor-positive cells via estrogen receptors and ERK1/2 activation in vitro and in vivo. Cancer Lett. 2011 Sep 28;308(2):144-51.

[相关活性小分子]

毛蕊异黄酮物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
536.8±50.0 °C at 760 mmHg

[ 分子式 ]:
C₁₆H₁₂O₅

[ 分子量 ]:
284.263

[ 闪点 ]:
205.7±23.6 °C

[ 精确质量 ]:
284.068481

[ PSA ]:
79.90000

[ LogP ]:
2.41

[ 外观性状 ]:
white to light yellow

[ 蒸汽压 ]:
0.0±1.5 mmHg at 25°C

[ 折射率 ]:
1.669

[ 储存条件 ]:
2-8°C

[ 水溶解性 ]:
methanol: soluble1mg/mL, clear, colorless

毛蕊异黄酮MSDS

毛蕊异黄酮安全信息

[ 符号 ]:

GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H301

[ 警示性声明 ]:
P301 + P310

[ 危害码 (欧洲) ]:
T

[ 风险声明 (欧洲) ]:
25

[ 安全声明 (欧洲) ]:
45

[ 危险品运输编码 ]:
UN 3462 6.1 / PGIII

[ 海关编码 ]:
2914509090

毛蕊异黄酮合成路线

毛蕊异黄酮海关

[ 海关编码 ]: 2914509090

[ 中文概述 ]:
2914509090 含其他含氧基的酮. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:5.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 丙酮报明包装

[ Summary ]:
HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

毛蕊异黄酮文献

Thermal stability of kudzu root (Pueraria Radix) isoflavones as additives to beef patties.

J. Food Sci. Technol. 52(3) , 1578-85, (2015)

Kudzu root, Pueraria radix, extracts are a rich source of isoflavones. This study investigates the thermal stability of Pueraria radix extracts as a natural nutraceutical supplement in beef patties. T...

Calycosin orchestrates the functions of Danggui Buxue Tang, a Chinese herbal decoction composing of Astragali Radix and Angelica Sinensis Radix: An evaluation by using calycosin-knock out herbal extract.

J. Ethnopharmacol. 168 , 150-7, (2015)

Danggui Buxue Tang (DBT) is a classical Chinese herbal decoction containing two herbs, Astragali Radix (AR) and Angelicae Sinensis Radix (ASR), which serves as dietary supplement for treating women me...

Protective effects of calycosin against CCl4-induced liver injury with activation of FXR and STAT3 in mice.

Pharm. Res. 32(2) , 538-48, (2015)

Investigating the hepatoprotective effect of calycosin against acute liver injury in association with FXR activation and STAT3 phosphorylation.The acute liver injury model was established by intraperi...

更多文献

毛蕊异黄酮

毛蕊异黄酮用途

毛蕊异黄酮名称

毛蕊异黄酮生物活性

毛蕊异黄酮物理化学性质

毛蕊异黄酮MSDS

详细MSDS(安全技术说明书)

毛蕊异黄酮安全信息

毛蕊异黄酮合成路线

详细合成路线

毛蕊异黄酮海关

毛蕊异黄酮文献

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