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苄基肼二盐酸盐

苄基肼二盐酸盐用途

苄基肼二盐酸盐名称

[ CAS 号 ]:
20570-96-1

[ 中文名 ]:
苄基肼二盐酸盐

[ 英文名 ]:
Benzylhydrazine dihydrochloride

[中文别名 ]:

[英文别名 ]:

EINECS 243-887-1
BENZYL HYDRAZINE di HCl
Benzylhydrazine dihydrochloride
1-benzylhydrazine dihydrochloride
Hydrazine,benzyl-,dihydrochloride
Hydrazine, (phenylmethyl)-, hydrochloride (1:2)
BnNHNH2*2HCl
N-benzylhydrazine dihydrochloride
(phenylmethyl)hydrazine dihydrochloride
benzylhydrazine*2HCl

苄基肼二盐酸盐物理化学性质

[ 密度 ]:
1.033g/cm3

[ 沸点 ]:
265.4ºC at 760 mmHg

[ 熔点 ]:
143-145 °C (dec.)(lit.)

[ 分子式 ]:
C₇H₁₂Cl₂N₂

[ 分子量 ]:
195.090

[ 闪点 ]:
132ºC

[ 精确质量 ]:
194.037750

[ PSA ]:
38.05000

[ LogP ]:
3.34510

[ 外观性状 ]:
略黄色至米色粉末

[ 储存条件 ]:
通风低温干燥,与库房食品原料分开存放

苄基肼二盐酸盐MSDS

苄基肼二盐酸盐毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MU8540000

CHEMICAL NAME :: Hydrazine, benzyl-, dihydrochloride

CAS REGISTRY NUMBER :: 20570-96-1

LAST UPDATED :: 198910

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C7-H10-N2.2Cl-H

MOLECULAR WEIGHT :: 195.11

WISWESSER LINE NOTATION :: ZM1R &GH 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 11 mg/kg

TOXIC EFFECTS :: Behavioral - changes in motor activity (specific assay) Behavioral - antipsychotic

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 10 gm/kg/29W-C

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors Blood - lymphoma, including Hodgkin's disease

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Bacteria - Bacillus subtilis

DOSE/DURATION :: 10 mmol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 5,343,1968

苄基肼二盐酸盐安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
UN 2811 6.1/PG 3

[ WGK德国 ]:
3

[ RTECS号 ]:
MU8540000

[ 危险类别 ]:
6.1

[ 海关编码 ]:
2928000090

苄基肼二盐酸盐合成路线

苄基肼二盐酸盐上下游产品

苄基肼二盐酸盐上游产品

苄基肼二盐酸盐下游产品

苄基肼二盐酸盐制备

苄基肼二盐酸盐海关

[ 海关编码 ]: 2928000090

[ 中文概述 ]:
2928000090 其他肼（联氨）及胲（羟胺）的有机衍生物。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

苄基肼二盐酸盐文献

Determination of hydrazine in pharmaceuticals IV: Hydrazine and benzylhydrazine in isocarboxazid.

J. Pharm. Sci. 74(1) , 105-7, (1985)

A GC procedure for the simultaneous determination of hydrazine and benzylhydrazine in isocarboxazid raw material and tablet formulations has been developed. The method is based on the reaction of benz...

Benzylhydrazine as a pseudo-substrate of bovine serum amine oxidase.

Biochem. J. 260(1) , 19-25, (1989)

Bovine serum amine oxidase is inhibited by benzylhydrazine (BHy), but recovers full activity after a few hours incubation [Hucko-Haas & Reed (1970) Biochem. Biophys. Res. Commun. 38, 396-400]. The fir...

Discovery and SAR of indole-2-carboxylic acid benzylidene-hydrazides as a new series of potent apoptosis inducers using a cell-based HTS assay.

Bioorg. Med. Chem. 12(13) , 3649-55, (2004)

A series of indole-2-carboxylic acid benzylidene-hydrazides has been identified as a new class of potent apoptosis inducers through a novel cell-based caspase HTS assay. The screening hit, 5-chloro-3-...

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