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二苯并[b,def]芘

二苯并[b,def]芘名称

[ CAS 号 ]:
189-64-0

[ 中文名 ]:
3,4:8,9-二苯并芘

[ 英文名 ]:
Dibenzochrysene

[中文别名 ]:

[英文别名 ]:

3,4:8,9-Dibenzpyrene
dibenzo[a,h]pyrene
dibenzo(a,h)pyrene
EINECS 205-878-0
3,4,8,9-Dibenzpyrene
Dibenzo[c,pqr]tetraphene
MFCD00039579
Dibenzo[b,def]chrysene
dibenzo<a,h>pyrene
3,4:8,9-Dibenzopyrene

二苯并[b,def]芘物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
552.3±17.0 °C at 760 mmHg

[ 熔点 ]:
308 °C

[ 分子式 ]:
C₂₄H₁₄

[ 分子量 ]:
302.368

[ 闪点 ]:
282.0±15.1 °C

[ 精确质量 ]:
302.109558

[ LogP ]:
7.63

[ 外观性状 ]:
固体;Light yellow to Amber to Dark green powder to crystal

[ 蒸汽压 ]:
0.0±0.7 mmHg at 25°C

[ 折射率 ]:
1.913

[ 储存条件 ]:
2-8°C

[ 水溶解性 ]:
可溶于：硫酸,二噁烷

二苯并[b,def]芘MSDS

二苯并[b,def]芘毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HO5775000

CHEMICAL NAME :: Dibenzo(b,def)chrysene

CAS REGISTRY NUMBER :: 189-64-0

BEILSTEIN REFERENCE NO. :: 2054067

LAST UPDATED :: 199712

DATA ITEMS CITED :: 17

MOLECULAR FORMULA :: C24-H14

MOLECULAR WEIGHT :: 302.38

WISWESSER LINE NOTATION :: L D6 B66 O666 2AB A&J

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 96761 ug/kg

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Implant

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 287 mg/kg/30W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 72 mg/kg/9W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors Liver - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 330 mg/kg/15W

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 700 mg/kg/42W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors Skin and Appendages - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1060 mg/kg/44W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Rodent - hamster Lung

DOSE/DURATION :: 30 ug/L

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 42,1646,1982 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 3,207,1973 IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 32,331,1983 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 32,331,1983 IARC Cancer Review:Group 2B IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 TOXICOLOGY REVIEW 85DHAX "Medical and Biologic Effects of Environmental Pollutants Series," Washington, DC, National Academy of Sciences, 1972-77 Volume(issue)/page/year: Pc,4,1972 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-FRANCE;Carcinogen JAN 1993

二苯并[b,def]芘安全信息

[ 符号 ]:

GHS02, GHS07, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H225-H304-H315-H319-H335-H336-H340-H350-H372

[ 警示性声明 ]:
P201-P210-P261-P301 + P310-P305 + P351 + P338-P308 + P313

[ 危害码 (欧洲) ]:
F: Flammable;T: Toxic;

[ 风险声明 (欧洲) ]:
R45

[ 安全声明 (欧洲) ]:
S53-S26-S36/37-S62

[ 危险品运输编码 ]:
2811

[ RTECS号 ]:
HO5775000

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1(b)

[ 海关编码 ]:
2902909090

二苯并[b,def]芘合成路线

二苯并[b,def]芘上下游产品

二苯并[b,def]芘上游产品

二苯并[b,def]芘下游产品

二苯并[b,def]芘海关

[ 海关编码 ]: 2902909090

[ 中文概述 ]:
2902909090. 其他芳香烃. 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:2.0%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量

[ Summary ]:
2902909090 other aromatic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%

二苯并[b,def]芘文献

Polycyclic aromatic hydrocarbons: 15 Listings - benz[a]anthracene, benzo[b]fluoranthene, benzo[j]fluoranthene, benzo[k]fluoranthene, benzo[a]pyrene, dibenz[a,h]acridine, dibenz[a,j]acridine, dibenz[a,h]anthracene, 7H-dibenzo[c,g]carbazole, dibenzo[a,e]pyrene, dibenzo[a,h]pyrene, dibenzo[a,i]pyrene, dibenzo[a,l]pyrene, indeno[1,2,3-cd]pyrene, 5-methylchrysene.

Rep. Carcinog. 12 , 353-61, (2011)

Dibenzo[a,h]pyrene.

IARC Monogr. Eval. Carcinog. Risk Chem. Hum. 32 , 331-5, (1983)

Mutagenicity of the bay-region diol-epoxides and other benzo-ring derivatives of dibenzo(a,h)pyrene and dibenzo(a,i)pyrene.

Cancer Res. 41(7) , 2589-97, (1981)

The mutagenic activities of dibenzo(a,h)(pyrene, dibenzo(a,i)pyrene, and a total of 11 of their benzo-ring derivatives were evaluated in bacterial and mammalian cells in the absence or presence of a m...

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