1,3,4,5-Tetrahydro-7-chloro-5-phenyl-2H-1,4-benzodiazepin-2-one

名称

[ CAS 号 ]:
1824-69-7

[ 英文名 ]:
1,3,4,5-Tetrahydro-7-chloro-5-phenyl-2H-1,4-benzodiazepin-2-one

[英文别名 ]:

Ro 5-2181

物理化学性质

[ 密度 ]:
1.247g/cm3

[ 沸点 ]:
440.8ºC at 760 mmHg

[ 分子式 ]:
C₁₅H₁₃ClN₂O

[ 分子量 ]:
272.73000

[ 闪点 ]:
220.4ºC

[ 精确质量 ]:
272.07200

[ PSA ]:
41.13000

[ LogP ]:
3.43790

[ 蒸汽压 ]:
5.73E-08mmHg at 25°C

[ 折射率 ]:
1.597

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DF2275000

CHEMICAL NAME :: 2H-1,4-Benzodiazepin-2-one, 7-chloro-5-phenyl-1,3,4,5-tetrahydro-

CAS REGISTRY NUMBER :: 1824-69-7

BEILSTEIN REFERENCE NO. :: 0753609

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C15-H13-Cl-N2-O

MOLECULAR WEIGHT :: 272.75

WISWESSER LINE NOTATION :: T67 GMV JM&TJ CG KR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 154,131,1965

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 335 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,168,1972

安全信息

[ 海关编码 ]:
2933990090

海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%