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硼氘化钠

硼氘化钠用途

用作还原剂，制备氘代氨硼络合剂。

硼氘化钠名称

[ CAS 号 ]:
15681-89-7

[ 中文名 ]:
硼氘化钠

[ 英文名 ]:
sodium borodeuteride

[英文别名 ]:

MFCD00003519
EINECS 239-764-7
Sodium tetradeuterioboron
Sodium borodeuteride
sodium,tetradeuterioboranuide
Sodium Borohydride-d4

硼氘化钠生物活性

[ 描述 ]:

硼氘钠-d4是氘标记的硼氘钠[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[体外研究]

氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要作为药物开发过程中定量的示踪剂。头韵因其可能影响药物的药代动力学和代谢特征而受到关注[1]。

[参考文献]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

硼氘化钠物理化学性质

[ 密度 ]:
1.07

[ 熔点 ]:
300ºC

[ 分子式 ]:
BD₄Na

[ 分子量 ]:
41.85720

[ 精确质量 ]:
42.05550

[ 外观性状 ]:
白色至灰白色粉末

[ 储存条件 ]:
water-free area

[ 水溶解性 ]:
Soluble in liquid ammonia, amines and pyridine.

硼氘化钠MSDS

详细MSDS(安全技术说明书)

硼氘化钠安全信息

[ 符号 ]:

GHS02, GHS05, GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H260-H301-H311-H314

[ 警示性声明 ]:
P223-P231 + P232-P280-P301 + P310-P370 + P378-P422

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
F:Highlyflammable;T:Toxic;

[ 风险声明 (欧洲) ]:
R15;R25;R34

[ 安全声明 (欧洲) ]:
S28-S36/37/39-S45-S7/8

[ 危险品运输编码 ]:
UN 1426 4.3/PG 1

[ WGK德国 ]:
3

[ 包装等级 ]:
I

[ 危险类别 ]:
4.3

硼氘化钠文献

Characterization and immunomodulatory activities of polysaccharides from Spirogyra neglecta (Hassall) Kützing.

Biosci. Biotechnol. Biochem. 79 , 1644-53, (2015)

Sulfated polysaccharides (SP) isolated from freshwater green algae, Spirogyra neglecta (Hassall) Kützing, and fractionated SPs were examined to investigate their molecular characteristics and immunomo...

Simultaneous gas-chromatographic urinary measurement of sugar probes to assess intestinal permeability: use of time course analysis to optimize its use to assess regional gut permeability.

Clin. Chim. Acta 442 , 24-32, (2015)

Measurement of intestinal permeability is important in several diseases but currently several methods are employed. We sought to: (1) develop a new GC based method to measure urinary mannitol, lactulo...

Profiling pneumococcal type 3-derived oligosaccharides by high resolution liquid chromatography-tandem mass spectrometry.

J. Chromatogr. A. 1397 , 43-51, (2015)

Pneumococcal type-3 polysaccharide (Pn3P) is considered a major target for the development of a human vaccine to protect against Streptococcus pneumoniae infection. Thus, it is critical to develop met...

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