α-Synuclein (61-95) (human) trifluoroacetate salt

用途

α-Synuclein (61-95) (human) 是 α-突触核蛋白 (α-Synuclein) 的疏水核心区域,可诱导神经元细胞死亡。α-Synuclein (61-95) (human) 可用于神经退行性疾病的研究,包括阿尔茨海默病 (AD) 和帕金森病 (PD)。

名称

[ CAS 号 ]:
154040-19-4

[ 英文名 ]:
α-Synuclein (61-95) (human) trifluoroacetate salt

[英文别名 ]:

生物活性

[ 描述 ]:

α-Synuclein (61-95) (human) 是 α-突触核蛋白 (α-Synuclein) 的疏水核心区域,可诱导神经元细胞死亡。α-Synuclein (61-95) (human) 可用于神经退行性疾病的研究,包括阿尔茨海默病 (AD) 和帕金森病 (PD)。

[ 相关类别 ]:

研究领域 >> 神经疾病

[参考文献]

[1]. Tabner BJ, et al. Formation of hydrogen peroxide and hydroxyl radicals from A(beta) and alpha-synuclein as a possible mechanism of cell death in Alzheimer's disease and Parkinson's disease. Free Radic Biol Med. 2002 Jun 1;32(11):1076-83.  

[2]. Emadi S, et al. Inhibiting aggregation of alpha-synuclein with human single chain antibody fragments. Biochemistry. 2004 Mar 16;43(10):2871-8.

物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
2937.7±65.0 °C at 760 mmHg

[ 分子式 ]:
C141H235N39O49

[ 分子量 ]:
3260.61

[ 闪点 ]:
1730.4±34.3 °C

[ 精确质量 ]:
3258.709473

[ LogP ]:
-6.81

[ 蒸汽压 ]:
0.0±0.3 mmHg at 25°C

[ 折射率 ]:
1.553

[ 储存条件 ]:
−20°C

安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

文献

Suppression of Cpn10 increases mitochondrial fission and dysfunction in neuroblastoma cells.

PLoS ONE 9(11) , e112130, (2014)

To date, several regulatory proteins involved in mitochondrial dynamics have been identified. However, the precise mechanism coordinating these complex processes remains unclear. Mitochondrial chapero...

Ellipticine induces apoptosis in T-cell lymphoma via oxidative DNA damage.

Leuk. Lymphoma 56(3) , 739-47, (2015)

The tumor suppressor p53 is often mutated in human cancers. Restoring its antitumor activity has been shown to be a promising therapeutic approach for cancer treatment. Here we analyzed the activity a...

Antiviral effect of methylated flavonol isorhamnetin against influenza.

PLoS ONE 10(3) , e0121610, (2015)

Influenza is an infectious respiratory disease with frequent seasonal epidemics that causes a high rate of mortality and morbidity in humans, poultry, and animals. Influenza is a serious economic conc...


更多文献

推荐生产厂家/供应商:

暂无推荐供应商。请联系客服获知如何成为推荐供应商。


相关化合物

CAS号[154040-19-4]化源网提供[α-Synuclein (61-95) (human) trifluoroacetate salt]MSDS、说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。>>电脑版:α-Synuclein (61-95) (human) trifluoroacetate salt

标题:【α-Synuclein (61-95) (human) trifluoroacetate salt】α-Synuclein (61-95) (human) trifluoroacetate salt CAS号:154040-19-4【结构式 性质 活性】-化源网 地址:https://www.chemsrc.com/amp/cas/154040-19-4_1548709.html