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银杏内酯B

银杏内酯B用途

银杏内酯B (Ginkgolide B)是一种萜类物质,是银杏叶中的重要的活性物质之一。

银杏内酯B名称

[ CAS 号 ]:
15291-77-7

[ 中文名 ]:
银杏内酯B

[ 英文名 ]:
Ginkgolide B

[中文别名 ]:

[英文别名 ]:

ginkgolide b from ginkgo biloba leaves
7-DEOXYGINKGOLIDE C
3-tert-butyl hexahydro-4,-7b-11 hydroxy-8-methyl
MFCD05662347
ginkgolide B from ginkgo leaves
GinkgolideB

银杏内酯B生物活性

[ 描述 ]:

银杏内酯B (Ginkgolide B)是一种萜类物质,是银杏叶中的重要的活性物质之一。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 其他

天然产物 >> 萜类化合物和糖苷

[参考文献]

[1]. Jean R. Rapin, et al. In vitro and in vivo effects of an extract of Ginkgo biloba (EGb 761), ginkgolide B, and bilobalide on apoptosis in primary cultures of rat hippocampal neurons. Drug Development Research, 1998, 45 (1):1-43

[2]. Matyas Koltai, et al. Ginkgolide B protects isolated hearts against arrhythmias induced by ischemia but not reperfusion. European Journal of Pharmacology, 1989, 164 (2): 293-302

[相关活性小分子]

银杏内酯B物理化学性质

[ 密度 ]:
1.6±0.1 g/cm3

[ 沸点 ]:
762.4±60.0 °C at 760 mmHg

[ 熔点 ]:
280°C (dec.)

[ 分子式 ]:
C₂₀H₂₄O₁₀

[ 分子量 ]:
424.399

[ 闪点 ]:
274.3±26.4 °C

[ 精确质量 ]:
424.136932

[ PSA ]:
148.82000

[ LogP ]:
0.52

[ 外观性状 ]:
白色晶体粉末

[ 蒸汽压 ]:
0.0±5.8 mmHg at 25°C

[ 折射率 ]:
1.651

[ 储存条件 ]:
2-8°C

银杏内酯B安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 安全声明 (欧洲) ]:
24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

银杏内酯B合成路线

详细合成路线

银杏内酯B上下游产品

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银杏内酯B文献

Complete 1H NMR spectral analysis of ten chemical markers of Ginkgo biloba.

Magn. Reson. Chem. 50(8) , 569-75, (2012)

The complete and unambiguous (1)H NMR assignments of ten marker constituents of Ginkgo biloba are described. The comprehensive (1)H NMR profiles (fingerprints) of ginkgolide A, ginkgolide B, ginkgolid...

Mechanistic evaluation of Ginkgo biloba leaf extract-induced genotoxicity in L5178Y cells.

Toxicol. Sci. 139(2) , 338-49, (2014)

Ginkgo biloba has been used for many thousand years as a traditional herbal remedy and its extract has been consumed for many decades as a dietary supplement. Ginkgo biloba leaf extract is a complex m...

Effects of Ginkgo biloba constituents on fruit-infesting behavior of codling moth (Cydia pomonella) in apples.

J. Agric. Food Chem. 59(20) , 10879-86, (2011)

Codling moth, Cydia pomonella (L.), is a cosmopolitan pest of apple, potentially causing severe damage to the fruit. Currently used methods of combating this insect do not warrant full success or are ...

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