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L-别异亮氨酸

L-别异亮氨酸用途

L-Alloisoleucine 是一种支链氨基酸,是 L-异亮氨酸的立体异构体,是人血浆的常见成分 (尽管水平较低)。

L-别异亮氨酸名称

[ CAS 号 ]:
1509-34-8

[ 中文名 ]:
L-别异亮氨酸

[ 英文名 ]:
L-allo-Isoleucine

[中文别名 ]:

[英文别名 ]:

Isoleucine, allo-
Alloisoleucine, L-
UNII:05T3WT3PJ1
L-Alloisoleucine
alle
Alloisoleucine
(2S,3R)-2-Amino-3-methylpentanoic acid
Allo-L-isoleucine
L-Isoleucine
l-aIle

L-别异亮氨酸生物活性

[ 描述 ]:

L-Alloisoleucine 是一种支链氨基酸,是 L-异亮氨酸的立体异构体,是人血浆的常见成分 (尽管水平较低)。

[ 相关类别 ]:

天然产物 >> 其他

研究领域 >> 其他

[ 靶点 ]

Human Endogenous Metabolite

[相关活性小分子]

L-别异亮氨酸物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
225.8±23.0 °C at 760 mmHg

[ 熔点 ]:
-285ºC

[ 分子式 ]:
C₆H₁₃NO₂

[ 分子量 ]:
131.173

[ 闪点 ]:
90.3±22.6 °C

[ 精确质量 ]:
131.094635

[ PSA ]:
63.32000

[ LogP ]:
0.73

[ 蒸汽压 ]:
0.0±0.9 mmHg at 25°C

[ 折射率 ]:
1.463

[ 储存条件 ]:
Store at RT.

L-别异亮氨酸MSDS

详细MSDS(安全技术说明书)

L-别异亮氨酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BA2933000

CHEMICAL NAME :: Alloisoleucine, L-

CAS REGISTRY NUMBER :: 1509-34-8

BEILSTEIN REFERENCE NO. :: 1721791

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C6-H13-N-O2

MOLECULAR WEIGHT :: 131.20

WISWESSER LINE NOTATION :: QVYZY2&1 -L,ALLO

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 6954 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - body temperature decrease

REFERENCE :: ABBIA4 Archives of Biochemistry and Biophysics. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.31- 1951- Volume(issue)/page/year: 58,253,1955

L-别异亮氨酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
26-36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
BA2933000

L-别异亮氨酸上下游产品

L-别异亮氨酸上游产品

L-别异亮氨酸下游产品

L-别异亮氨酸文献

Interrelation between the metabolism of L-isoleucine and L-allo-isoleucine in patients with maple syrup urine disease.

Pediatr. Res. 25 , 11-14, (1989)

The nonprotein amino acid L-allo-isoleucine is formed endogenously in maple syrup urine disease patients from (R)-3-methyl-2-oxo-pentanoic acid. During strict metabolic balance, the plasma L-allo-isol...

Functional differences in the catabolism of branched-chain L-amino acids in cultured normal and maple syrup urine disease fibroblasts.

Biochem. Med. Metab. Biol. 41 , 105-116, (1989)

Possible functional differences in the catabolism of the four branched-chain L-amino acids in maple syrup urine disease were assessed using cultured human skin fibroblast stains. Transamination and ox...

Substrate specificity of L-delta-(alpha-aminoadipoyl)-L-cysteinyl-D-valine synthetase from Cephalosporium acremonium: demonstration of the structure of several unnatural tripeptide products.

Biochem. J. 301 , 367-372, (1994)

Potential substrates for L-delta-(alpha-aminoadipoyl)-L-(cysteinyl)-D-valine (ACV) synthetase were initially identified using both the amino-acid-dependent ATP<-->pyrophosphate exchange reaction catal...

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