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(1R,2S)-1-氨基-2-茚醇

(1R,2S)-1-氨基-2-茚醇用途

(1R,2S)-1-氨基-2-茚醇是一种生物化学试剂,可作为生物材料或有机化合物用于生命科学相关研究。

(1R,2S)-1-氨基-2-茚醇名称

[ CAS 号 ]:
136030-00-7

[ 中文名 ]:
(1R,2S)-1-氨基-2-茚醇

[ 英文名 ]:
(1R,2S)-1-Amino-2,3-dihydro-1H-inden-2-ol

[中文别名 ]:

[英文别名 ]:

(1R,2S)-1-amino-2,3-dihydro-1H-inden-2-ol
(1R,2S)-1-Aminoindan-2-ol
MFCD00216656
(1R,2S)-(+)-cis-1-Amino-2-hydroxyindane
1H-Inden-2-ol, 1-amino-2,3-dihydro-, (1R,2S)-
(1R,2S)-(+)-1-Amino-2-indanol
(1R,2S)-(+)-1-Amino-2-hydroxyindan
(1R,2S)-(+)-cis-1-amino-2-indanol
(1R,2S)-1-Amino-2-indanol
Cis-(1R,2S)-1-amino-2-indanol

(1R,2S)-1-氨基-2-茚醇生物活性

[ 描述 ]:

(1R,2S)-1-氨基-2-茚醇是一种生物化学试剂,可作为生物材料或有机化合物用于生命科学相关研究。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

(1R,2S)-1-氨基-2-茚醇物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
290.0±40.0 °C at 760 mmHg

[ 熔点 ]:
117-121ºC

[ 分子式 ]:
C₉H₁₁NO

[ 分子量 ]:
149.19

[ 闪点 ]:
129.2±27.3 °C

[ 精确质量 ]:
149.084061

[ PSA ]:
46.25000

[ LogP ]:
0.43

[ 外观性状 ]:
白色至淡黄色晶体粉末

[ 蒸汽压 ]:
0.0±0.6 mmHg at 25°C

[ 折射率 ]:
1.626

[ 储存条件 ]:
存放于惰性气体之中;避免空气

[ 水溶解性 ]:
可溶于：甲醇

(1R,2S)-1-氨基-2-茚醇MSDS

(1R,2S)-1-氨基-2-茚醇安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn

[ 风险声明 (欧洲) ]:
R20/21/22;R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36/37/39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2922199090

(1R,2S)-1-氨基-2-茚醇合成路线

(1R,2S)-1-氨基-2-茚醇上下游产品

(1R,2S)-1-氨基-2-茚醇上游产品

(1R,2S)-1-氨基-2-茚醇下游产品

(1R,2S)-1-氨基-2-茚醇海关

[ 海关编码 ]: 2922199090

[ 中文概述 ]:
2922199090. 其他氨基醇及其醚，酯和它们的盐（但含一种以上含氧基的除外）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

(1R,2S)-1-氨基-2-茚醇文献

A series of potent HIV-1 protease inhibitors containing a hydroxyethyl secondary amine transition state isostere: synthesis, enzyme inhibition, and antiviral activity.

J. Med. Chem. 35 , 2525, (1992)

A series of HIV-1 protease inhibitors containing a novel hydroxyethyl secondary amine transition state isostere has been synthesized. The compounds exhibit a strong preference for the (R) stereochemis...

Synthesis and antiviral activity of a series of HIV-1 protease inhibitors with functionality tethered to the P1 or P1' phenyl substituents: X-ray crystal structure assisted design.

J. Med. Chem. 35 , 1685, (1992)

By tethering of a polar hydrophilic group to the P1 or P1' substituent of a Phe-based hydroxyethylene isostere, the antiviral potency of a series of HIV protease inhibitors was improved. The optimum e...

HIV-1 protease inhibitors based on hydroxyethylene dipeptide isosteres: an investigation into the role of the P1' side chain on structure-activity.

J. Med. Chem. 35 , 1702, (1992)

A systematic investigation was undertaken to determine the role of the P1' sidechain in a series of hydroxyethylene isostere based inhibitors of HIV-1 protease. Substitution and homologation of the be...

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