<生产厂家价格>

2,6-二叔丁基苯酚

2,6-二叔丁基苯酚用途

主要用于制造天然橡胶及合成胶防老剂，塑料抗氧剂，燃料稳定剂，紫外线吸收剂及农药、染料中间体等，主要品种有抗氧剂1010、1076、702、3114、4426、甲叉4426-S、2002、330、1098、1088等。

2,6-二叔丁基苯酚名称

[ CAS 号 ]:
128-39-2

[ 中文名 ]:
2,6-二叔丁基苯酚

[ 英文名 ]:
2,6-Di-tert-butylphenol

[中文别名 ]:

[英文别名 ]:

MFCD00008820
Phenol, 2,6-bis(1,1-dimethylethyl)-
2,6-Bis(2-methyl-2-propanyl)phenol
EINECS 204-884-0
2,6-bis(1,1-Dimethylethyl)phenol
2,6-ditert-butylphenol
2,6-Di-tert-butylphenol

2,6-二叔丁基苯酚物理化学性质

[ 密度 ]:
0.9±0.1 g/cm3

[ 沸点 ]:
251.4±9.0 °C at 760 mmHg

[ 熔点 ]:
34-37 °C(lit.)

[ 分子式 ]:
C₁₄H₂₂O

[ 分子量 ]:
206.324

[ 闪点 ]:
118.3±0.0 °C

[ 精确质量 ]:
206.167068

[ PSA ]:
20.23000

[ LogP ]:
4.86

[ 外观性状 ]:
透明至淡黄色半固体

[ 蒸汽压 ]:
0.0±0.5 mmHg at 25°C

[ 折射率 ]:
1.499

[ 储存条件 ]:
2-8°C

[ 稳定性 ]:
Stable. Incompatible with acid chlorides, acid anhydrides, bases, brass, copper, copper alloys, oxidizing agents.

[ 水溶解性 ]:
insoluble

2,6-二叔丁基苯酚MSDS

2,6-二叔丁基苯酚毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SK8265000

CHEMICAL NAME :: Phenol, 2,6-di-tert-butyl-

CAS REGISTRY NUMBER :: 128-39-2

LAST UPDATED :: 199710

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C14-H22-O

MOLECULAR WEIGHT :: 206.36

WISWESSER LINE NOTATION :: QR BX1&1&1 FX1&1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0526583

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 120 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 23,1350,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0526583

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0526583 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 19708 mg/kg/3W-C

TOXIC EFFECTS :: Gastrointestinal - hypermotility, diarrhea Blood - change in clotting factors Related to Chronic Data - death

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 46,811,1978

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 12480 ng/kg/12D-C

TOXIC EFFECTS :: Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other transferases

REFERENCE :: BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 45,935,1982 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M4376 No. of Facilities: 196 (estimated) No. of Industries: 9 No. of Occupations: 12 No. of Employees: 2192 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M4376 No. of Facilities: 13899 (estimated) No. of Industries: 175 No. of Occupations: 97 No. of Employees: 365623 (estimated) No. of Female Employees: 72928 (estimated)

2,6-二叔丁基苯酚安全信息

[ 符号 ]:

GHS07, GHS09

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H410

[ 警示性声明 ]:
P273-P501

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn:Harmful;N:Dangerousfortheenvironment;

[ 风险声明 (欧洲) ]:
R22;R51/53

[ 安全声明 (欧洲) ]:
S26-S36-S61-S29

[ 危险品运输编码 ]:
UN 3145 8/PG 3

[ WGK德国 ]:
2

[ RTECS号 ]:
SK8265000

[ 包装等级 ]:
III

[ 危险类别 ]:
9

[ 海关编码 ]:
2907199090

2,6-二叔丁基苯酚合成路线

2,6-二叔丁基苯酚上下游产品

2,6-二叔丁基苯酚上游产品

2,6-二叔丁基苯酚下游产品

2,6-二叔丁基苯酚制备

2,6-二叔丁基苯酚海关

[ 海关编码 ]: 2907199090

[ 中文概述 ]:
2907199090 其他一元酚. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:5.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2907199090 other monophenols VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

2,6-二叔丁基苯酚文献

Cellular apoptosis and cytotoxicity of phenolic compounds: a quantitative structure-activity relationship study.

J. Med. Chem. 48 , 7234-42, (2005)

In this comprehensive study on the caspase-mediated apoptosis-inducing effect of 51 substituted phenols in a murine leukemia cell line (L1210), we determined the concentrations needed to induce caspas...

Carbonic anhydrase inhibitors. Inhibition of human erythrocyte isozymes I and II with a series of antioxidant phenols.

Bioorg. Med. Chem. 17 , 3207-11, (2009)

The inhibition of two human cytosolic carbonic anhydrase (hCA, EC 4.2.1.1) isozymes I and II, with a series of phenol derivatives was investigated by using the esterase assay, with 4-nitrophenyl aceta...

Antioxidant activity of propofol and related monomeric and dimeric compounds.

Chem. Pharm. Bull. 53(3) , 344-6, (2005)

This study was carried out to investigate the antioxidant activity of propofol (2,6-diisopropylphenol) and its related compounds, butylated hydroxyanisole (BHA), 2,6-dimethylphenol, 2,6-di-t-butylphen...

更多文献