NALTRINDOLE ISOTHIOCYANATE

[ 密度 ]:
1.68g/cm3

[ 沸点 ]:
718.7ºC at 760mmHg

[ 分子式 ]:
C₂₇H₂₅N₃O₃S

[ 分子量 ]:
471.57100

[ 闪点 ]:
388.5ºC

[ 精确质量 ]:
471.16200

[ PSA ]:
113.17000

[ LogP ]:
4.24480

[ 蒸汽压 ]:
1.12E-21mmHg at 25°C

[ 折射率 ]:
1.882

详细MSDS(安全技术说明书)

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

Alkylation of opioid receptors by 5'-naltrindole-isothiocyanate injected into the nucleus accumbens of rats: receptor selectivity and anatomical diffusion.

Synapse 60(5) , 384-91, (2006)

Subtypes of the delta opioid receptor (Oprd1) have been suggested based on pharmacology studies. However, these subtypes have not been confirmed biochemically using either receptor binding assays or m...

Microinjection of the delta-opioid receptor selective antagonist naltrindole 5'-isothiocyanate site specifically affects cocaine self-administration in rats responding under a progressive ratio schedule of reinforcement.

Behav. Brain Res. 182(1) , 140-4, (2007)

Whether the delta-opioid receptor (DOR) system can modulate behavioral effects of cocaine remains equivocal. We examined whether site- and subtype-selective blockade of DORs within the rat mesocortico...

Evidence for chemical differentiation of delta opioid receptor subtypes by the sulfhydryl reagent N-ethylmaleimide.

Receptor 4(2) , 81-91, (1994)

In this study, the delta receptor-selective nonequilibrium affinity ligands, 5'-NTII and DALCE, and the nonspecific sulfhydryl reagent NEM were evaluated over a range of concentrations and treatment c...

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