阿替夫林
阿替夫林名称
[ CAS 号 ]:
123407-36-3
[ 中文名 ]:
阿替夫林
[ 英文名 ]:
ARTEFLENE
[英文别名 ]:
- Arteflene (USAN/INN)
- Ro 42-1611
- UNII-5PE5HV9NF0
- C19H18F6O3
- Arteflene
阿替夫林物理化学性质
[ 密度 ]:
1.348g/cm3
[ 沸点 ]:
366.7ºC at 760mmHg
[ 分子式 ]:
C19H18F6O3
[ 分子量 ]:
408.33500
[ 闪点 ]:
169.6ºC
[ 精确质量 ]:
408.11600
[ PSA ]:
35.53000
[ LogP ]:
5.44170
[ 蒸汽压 ]:
1.43E-05mmHg at 25°C
[ 折射率 ]:
1.507
阿替夫林毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- JG6813000
- CHEMICAL NAME :
- 2,3-Dioxabicyclo(3.3.1)nonan-7-one, 4-(2-(2,4-bis(trifluoromethyl)phenyl)ethenyl)-4,8- dimethyl-, (1S-(1-alpha,4-beta(Z),5-alpha,8-beta))-
- CAS REGISTRY NUMBER :
- 123407-36-3
- LAST UPDATED :
- 199606
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C19-H18-F6-O3
- MOLECULAR WEIGHT :
- 408.37
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TMPRAD Tropenmedizin und Parasitologie. (Georg Thieme Verlag, Postfach 732, D-7000 Stuttgart 1, Fed. Rep. Ger.) V.25- 1974- Volume(issue)/page/year: 45,261,1994
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Skin and Appendages - dermatitis, other (after systemic exposure)
- REFERENCE :
- TMPRAD Tropenmedizin und Parasitologie. (Georg Thieme Verlag, Postfach 732, D-7000 Stuttgart 1, Fed. Rep. Ger.) V.25- 1974- Volume(issue)/page/year: 45,261,1994
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >2500 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Nutritional and Gross Metabolic - body temperature decrease
- REFERENCE :
- TMPRAD Tropenmedizin und Parasitologie. (Georg Thieme Verlag, Postfach 732, D-7000 Stuttgart 1, Fed. Rep. Ger.) V.25- 1974- Volume(issue)/page/year: 45,261,1994
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >2500 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- REFERENCE :
- TMPRAD Tropenmedizin und Parasitologie. (Georg Thieme Verlag, Postfach 732, D-7000 Stuttgart 1, Fed. Rep. Ger.) V.25- 1974- Volume(issue)/page/year: 45,261,1994
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