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L-亮氨酰甘氨酰甘氨酸

L-亮氨酰甘氨酰甘氨酸用途

(S) -2-(2-(2-氨基-4-甲基戊酰胺)乙酰胺)乙酸是一种甘氨酸(HY-Y0966)衍生物[1]。

L-亮氨酰甘氨酰甘氨酸名称

[ CAS 号 ]:
1187-50-4

[ 中文名 ]:
L-亮氨酰甘氨酰甘氨酸

[ 英文名 ]:
H-Leu-Gly-Gly-OH

[英文别名 ]:

L-Leucylglycylglycine
H-LEU-GLY-GLY-OH
(L)-leucyl-glycylglycine
L-Leucyl-glycyl-glycine,L-leucylglycylglycine
N-(N-L-leucylglycyl)glycine
N-[(S)-2-Amino-4-methylpentanoyl]-Gly-Gly-OH
Glycine,N-(N-L-leucylglycyl)
EINECS 219-925-8
L-LeucylglycylglycineA.R.
MFCD00065942

L-亮氨酰甘氨酰甘氨酸生物活性

[ 描述 ]:

(S) -2-(2-(2-氨基-4-甲基戊酰胺)乙酰胺)乙酸是一种甘氨酸(HY-Y0966)衍生物[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[体外研究]

氨基酸和氨基酸衍生物已被商业化用作能量补充剂。它们影响合成代谢激素的分泌、运动期间的燃料供应、压力相关任务期间的精神表现,并防止运动引起的肌肉损伤。它们被认为是有益的能生膳食物质[1]。

[参考文献]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

L-亮氨酰甘氨酰甘氨酸物理化学性质

[ 密度 ]:
1.199g/cm3

[ 沸点 ]:
573.7ºC at 760mmHg

[ 熔点 ]:
-220ºC (dec.)

[ 分子式 ]:
C₁₀H₁₉N₃O₄

[ 分子量 ]:
245.27600

[ 闪点 ]:
300.8ºC

[ 精确质量 ]:
245.13800

[ PSA ]:
121.52000

[ LogP ]:
0.15890

[ 蒸汽压 ]:
1.17E-14mmHg at 25°C

[ 折射率 ]:
1.504

[ 储存条件 ]:
−20°C

L-亮氨酰甘氨酰甘氨酸MSDS

L-亮氨酰甘氨酰甘氨酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2924199090

L-亮氨酰甘氨酰甘氨酸合成路线

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L-亮氨酰甘氨酰甘氨酸下游产品

L-亮氨酰甘氨酰甘氨酸海关

[ 海关编码 ]: 2924199090

[ 中文概述 ]:
2924199090. 其他无环酰胺（包括无环氨基甲酸酯)(包括其衍生物及盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

L-亮氨酰甘氨酰甘氨酸文献

Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.

Nat. Chem. Biol. 5 , 45-52, (2009)

Transporter-related nutrient sensors, called transceptors, mediate nutrient activation of signaling pathways through the plasma membrane. The mechanism of action of transporting and nontransporting tr...

Three-dimensional quantitative structure-activity relationship analyses of beta-lactam antibiotics and tripeptides as substrates of the mammalian H+/peptide cotransporter PEPT1.

J. Med. Chem. 48 , 4410-9, (2005)

The utilization of the membrane transport protein PEPT1 as a drug delivery system is a promising strategy to enhance the oral bioavailability of drugs. Since very little is known about the substrate b...

Fragmental modeling of hPepT2 and analysis of its binding features by docking studies and pharmacophore mapping.

Bioorg. Med. Chem. 19 , 4544-51, (2011)

Over the last years, considerable progress has been made for the identification and characterization of drug transporters, and several modeling studies have been undertaken to predict their effects on...

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