<生产厂家价格>

反-1,4-二氯-2-丁烯

反-1,4-二氯-2-丁烯用途

【用途一】
反式-1,4-二氯-2-丁烯（110-57-6）用于合成吡咯芬。同时也用于己二腈、丁二醇、六亚甲基二胺、氯丁二烯、四氢呋喃的生产。

反-1,4-二氯-2-丁烯名称

[ CAS 号 ]:
110-57-6

[ 中文名 ]:
反式1.4-二氯-2-丁烯

[ 英文名 ]:
trans-1,4-Dichlorobutene

[中文别名 ]:

[英文别名 ]:

2-Butene, 1,4-dichloro-, (E)-
Toluene,2,5-dichloro
trans-1,4-Dichlorobutene
(2E)-1,4-Dichloro-2-butene
1,4-Dichloro-2-butene
Benzene,1,4-dichloro-2-methyl
trans 1,4-Dichloro-2-butene
(E)-1,4-Dichloro-2-butene
EINECS 203-779-7
TRANS-1,4-DICHLORO-2-BUTYLENE

反-1,4-二氯-2-丁烯物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
155.5±0.0 °C at 760 mmHg

[ 熔点 ]:
1-3ºC(lit.)

[ 分子式 ]:
C₄H₆Cl₂

[ 分子量 ]:
124.996

[ 闪点 ]:
54.4±0.0 °C

[ 精确质量 ]:
123.984657

[ LogP ]:
1.97

[ 外观性状 ]:
无色液体带有一种独特的气味

[ 蒸汽压 ]:
3.9±0.2 mmHg at 25°C

[ 折射率 ]:
1.459

[ 储存条件 ]:
库房通风低温干燥,与食品原料分开存放

[ 水溶解性 ]:
水溶性：不溶；水溶解度：850 mg/l 25 °C；可溶于：苯,乙醚,氯仿,丙酮,醇

反-1,4-二氯-2-丁烯MSDS

反-1,4-二氯-2-丁烯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: EM4903000

CHEMICAL NAME :: 2-Butene, 1,4-dichloro-, (E)-

CAS REGISTRY NUMBER :: 110-57-6

BEILSTEIN REFERENCE NO. :: 1719693

LAST UPDATED :: 199712

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C4-H6-Cl2

MOLECULAR WEIGHT :: 125.00

WISWESSER LINE NOTATION :: G2U2G -T

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 86 ppm/4H

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - lacrimation Lungs, Thorax, or Respiration - other changes Gastrointestinal - changes in structure or function of salivary glands

REFERENCE :: AIHAM* Annual Meeting of American Industrial Hygiene Association. (Akron, OH) For publisher information, see AIHAAP. Volume(issue)/page/year: -,-,1968 ** TUMORIGENIC DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 150 mg/kg/77W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 35,2553,1975

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 150 mg/kg/77W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 35,2553,1975 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,149,1977 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,149,1977 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987

反-1,4-二氯-2-丁烯安全信息

[ 符号 ]:

GHS02, GHS05, GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H226-H301-H312-H314-H330

[ 警示性声明 ]:
P260-P280-P284-P305 + P351 + P338-P310

[ 个人防护装备 ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
T+,T,F,N

[ 风险声明 (欧洲) ]:
R10

[ 安全声明 (欧洲) ]:
53-23-26-36/37/39-45-36/37-99-61-60

[ 危险品运输编码 ]:
UN 3390 6.1/PG 1

[ WGK德国 ]:
3

[ RTECS号 ]:
EM4903000

[ 包装等级 ]:
II

[ 危险类别 ]:
6.1(a)

[ 海关编码 ]:
2903299090

反-1,4-二氯-2-丁烯合成路线

反-1,4-二氯-2-丁烯上下游产品

反-1,4-二氯-2-丁烯上游产品

反-1,4-二氯-2-丁烯下游产品

反-1,4-二氯-2-丁烯海关

[ 海关编码 ]: 2903299090

[ 中文概述 ]:
HS: 2903299090. 其他无环烃的不饱和氯化衍生物. 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:5.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2903299090 other unsaturated chlorinated derivatives of acyclic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

反-1,4-二氯-2-丁烯文献

Halogenated derivatives QSAR model using spectral moments to predict haloacetic acids (HAA) mutagenicity.

Bioorg. Med. Chem. 16 , 5720-32, (2008)

The risk of the presence of haloacetic acids in drinking water as chlorination by-products and the shortage of experimental mutagenicity data for most of them requires a research work. This paper desc...

Synthesis and biological properties of 9-(trans-4-hydroxy-2-buten-1-yl)adenine and guanine: open-chain analogues of neplanocin A.

J. Med. Chem. 30(2) , 437-40, (1987)

Alkylation of adenine (5a) or 2-amino-6-chloropurine (5b) with excess trans-1,4-dichloro-2-butene (4), effected by K2CO3 in dimethyl sulfoxide or tetra-n-butylammonium fluoride in tetrahydrofuran, led...

Effect of isomers of swainsonine on glycosidase activity and glycoprotein processing.

Biochemistry 26(9) , 2502-10, (1987)

The chemical synthesis of swainsonine [(1S,2R,8R,8 alpha R)-trihydroxyindolizidine] from trans-1,4-dichloro-2-butene was previously described [Adams, C. E., Walker, F. J., & Sharpless, K. B. (1985) J....

更多文献