乙烯基乙醚

乙烯基乙醚用途

【用途一】
医药上用作麻醉剂、镇痛剂，也用作精细化学品的中间体
【用途二】
乙烯基乙醚麻痹中枢神经，其麻醉作用比乙醚强，因此医药上用作麻醉剂、镇痛剂。该品还是精细化学品的中间体，可用于药物磺胺嘧啶、消毒剂戊二醛、聚合物、涂料等的生产。也可用于制取香料及润滑油添加剂等。
【用途三】
乙烯基乙醚麻痹中枢神经，其麻醉作用比乙醚强，因此医药上用作麻醉剂、镇痛剂。该品还是精细化学品的中间体，可用于药物磺胺嘧啶、消毒剂戊二醛、聚合物、涂料等的生产。也可用于制取香料及润滑油添加剂等

乙烯基乙醚名称

[ CAS 号 ]:
109-92-2

[ 中文名 ]:
乙烯基乙醚

[ 英文名 ]:
Ethoxyethene

[中文别名 ]:

[英文别名 ]:

vinyl ethyl dichloro silane
Aethyl-dichlor-vinyl-silan
Ethyl ethenyl ether
dichloroethenylethyl-silan
ethyl vinyl ether
dichloroethylvinylsilane
4-01-00-02049 (Beilstein Handbook Reference)
1-Ethoxyethene
UNII-6235C9592H
Ether, vinyl ethyl

乙烯基乙醚物理化学性质

[ 密度 ]:
0.8±0.1 g/cm3

[ 沸点 ]:
32.5±9.0 °C at 760 mmHg

[ 熔点 ]:
−116 °C(lit.)

[ 分子式 ]:
C₄H₈O

[ 分子量 ]:
72.106

[ 闪点 ]:
-45.6±0.0 °C

[ 精确质量 ]:
72.057518

[ PSA ]:
9.23000

[ LogP ]:
1.04

[ 外观性状 ]:
透明无色液体

[ 蒸汽压 ]:
581.4±0.1 mmHg at 25°C

[ 折射率 ]:
1.376

[ 储存条件 ]:
库房通风低温干燥,与氧化剂、酸类分开存放

[ 稳定性 ]:
Stable. Highly flammable. Incompatible with strong oxidizing agents. May form peroxides in storage - check for their formation before use.

[ 水溶解性 ]:
7.8 g/L (25 ºC)

乙烯基乙醚MSDS

详细MSDS(安全技术说明书)

乙烯基乙醚毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KO0710000

CHEMICAL NAME :: Ether, ethyl vinyl

CAS REGISTRY NUMBER :: 109-92-2

BEILSTEIN REFERENCE NO. :: 0605351

LAST UPDATED :: 199701

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C4-H8-O

MOLECULAR WEIGHT :: 72.12

WISWESSER LINE NOTATION :: 2O1U1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 8160 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 16000 ppm/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >20 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GAFCC* GAF Material Safety Data Sheet. (GAF Chemicals Corporation, 1361 Alps Road, Wayne, NJ 07470)

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 324 gm/m3/15M

TOXIC EFFECTS :: Behavioral - general anesthetic

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >20 mL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 17900 ppm

REFERENCE :: ANESAV Anesthesiology. (Lippincott/Harper, Journal Fulfillment Dept., 2350 Virginia Ave., Hagerstown, MD 21740) V.1- 1940- Volume(issue)/page/year: 50,426,1979

乙烯基乙醚安全信息

[ 符号 ]:

GHS02, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H225-H315-H319-H335

[ 警示性声明 ]:
P210-P305 + P351 + P338-P370 + P378-P403 + P235

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US)

[ 危害码 (欧洲) ]:
F:Flammable

[ 风险声明 (欧洲) ]:
R12;R19;R36/37/38

[ 安全声明 (欧洲) ]:
S16-S23-S26-S3/7-S33-S36

[ 危险品运输编码 ]:
UN 1302 3/PG 1

[ WGK德国 ]:
1

[ RTECS号 ]:
KO0710000

[ 包装等级 ]:
I

[ 危险类别 ]:
3

[ 海关编码 ]:
2942000000

乙烯基乙醚合成路线

详细合成路线

乙烯基乙醚上下游产品

乙烯基乙醚上游产品

乙烯基乙醚下游产品

乙烯基乙醚制备

1.由电石发生乙炔，乙炔再与乙醇在氢氧化钾催化剂存在下，经加压反应制得。

精制方法：乙基乙烯基醚主要含有乙醇、乙醛、缩醛以及为防止水解而加入的三乙醇胺等杂质。精制方法是用水或稀氢氧化钾充分洗涤。过氧化物可用硫酸亚铁、亚硫酸钠、氯化亚锡等还原剂溶液洗涤，再用氢氧化钾、氯化钙干燥，加氢氧化钾或金属钠蒸馏精制。

2.制1一氯乙基乙基醚
将等摩尔量的聚乙醛和乙醇混合，冷却，通于燥抓化氢气使饱和。分出氯乙基醚粗品，保持在低温下，用无水氯化钙干燥2小时。干燥的时间长了将引起显著分解。最后在减压下吹入干燥空气约2小时，以赶尽产品中残余的氯化氢。产率94%。

制乙基乙烯基醚
在室温下，将24克(0.22摩尔)1一氯乙基乙基醚加到40毫升(0.5摩尔)毗咤中。蒸馏，在蒸汽温度达100℃前，可收集到14毫升馏出物。馏出物再经长1厘米的松针形分馏柱进行分馏，得到乙基乙烯醚，重6.8克(43%)。

3.制法：

于装有分馏柱（连接冷凝器，并接受瓶用冰盐浴冷却）的反应瓶中，加入无水乙醇50g（1.08mol）,醋酸汞5g（0.016mol），正丁基乙烯基醚（2）100g（1.0mol），加热回流。控制分馏柱顶部的温度在36～37℃，蒸出乙基乙烯基醚（1）71g，收率98%。于蒸馏瓶中加入水，共沸蒸馏（97℃），分离，得正丁醇71.2g，收率97%。

乙烯基乙醚海关

[ 海关编码 ]: 2909199090

[ 中文概述 ]:
2909199090. 其他无环醚及其卤化衍生物（包括磺化，硝化或亚硝化衍生物）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:5.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2909199090. other acyclic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

乙烯基乙醚文献

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J. Am. Chem. Soc. 136(35) , 12479-88, (2014)

Electrochemical studies are reported on a series of peptides constrained into either a 310-helix (1-6) or β-strand (7-9) conformation, with variable numbers of electron rich alkene containing side cha...

Well-defined diblock brush polymer-drug conjugates for sustained delivery of paclitaxel.

Biomater. Sci. 3 , 1078-84, (2015)

Using the 3(rd) generation Grubbs' catalyst as the initiator, diblock brush polymer drug conjugates (BPDCs) were synthesized by sequential ring-opening metathesis polymerization (ROMP) of a hydrophili...

Influence of Alkoxy Groups on the Photoinduced Dynamics of Organic Molecules Exemplified on Alkyl Vinyl Ethers.

J. Phys. Chem. A 119 , 11105-12, (2015)

A series of different alkyl vinyl ethers is investigated to decipher the possible reaction channels upon photoexcitation to the π3s-Rydberg and the ππ*-valence state at 200 nm using time-resolved phot...

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