二氯异乙醚

二氯异乙醚用途

用作脂、蜡、润滑脂的溶剂和去漆剂、去垢剂、萃取剂。

二氯异乙醚名称

[ CAS 号 ]:
108-60-1

[ 中文名 ]:
二氯异丙醚

[ 英文名 ]:
Propane,2,2'-oxybis[1-chloro-

[中文别名 ]:

[英文别名 ]:

EINECS 203-598-3
Bis(2-chloroisopropyl) Ether
2-Chloroisopropyl ether
2,2’-oxybis(1-chloropropane)
2,2’-oxybis[1-chloropropane]
bis(2-chloro-1-methylethyl) ether
BIS(2-CHLOROISOPROPYL)ETHER

二氯异乙醚物理化学性质

[ 密度 ]:
1.086 g/cm3

[ 沸点 ]:
187ºC at 760 mmHg

[ 熔点 ]:
-97 to -102ºC

[ 分子式 ]:
C₆H₁₂Cl₂O

[ 分子量 ]:
171.06500

[ 闪点 ]:
11 °C

[ 精确质量 ]:
170.02700

[ PSA ]:
9.23000

[ LogP ]:
2.95280

[ 外观性状 ]:
无色至棕色,油性液体

[ 蒸汽压 ]:
0.887mmHg at 25°C

[ 折射率 ]:
1.436

[ 储存条件 ]:
库房通风低温干燥,与食品原料分开储运

二氯异乙醚MSDS

二氯异乙醚毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KN1750000

CHEMICAL NAME :: Ether, bis(2-chloro-1-methylethyl)

CAS REGISTRY NUMBER :: 108-60-1

BEILSTEIN REFERENCE NO. :: 1735833

LAST UPDATED :: 199806

DATA ITEMS CITED :: 22

MOLECULAR FORMULA :: C6-H12-Cl2-O

MOLECULAR WEIGHT :: 171.08

WISWESSER LINE NOTATION :: G1Y1&OY1&1G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 240 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 700 ppm/5H

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - iritis Lungs, Thorax, or Respiration - dyspnea Liver - other changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 296 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 3 mL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 11250 mg/kg/45D-I

TOXIC EFFECTS :: Blood - pigmented or nucleated red blood cells Blood - changes in erythrocyte (RBC) count Blood - changes in leukocyte (WBC) count

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2340 mg/kg/26W-I

TOXIC EFFECTS :: Blood - changes in leukocyte (WBC) count Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other Enzymes

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 364 gm/kg/2Y-C

TOXIC EFFECTS :: Behavioral - food intake (animal) Blood - changes in spleen Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4424 mg/kg/14D-I

TOXIC EFFECTS :: Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 876 gm/kg/2Y-C

TOXIC EFFECTS :: Behavioral - food intake (animal) Nutritional and Gross Metabolic - weight loss or decreased weight gain

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 11300 ug/L

REFERENCE :: EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 10(Suppl 10),1,1987 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 41,149,1986 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 41,149,1986 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987

二氯异乙醚安全信息

[ 符号 ]:

GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H301-H332

[ 警示性声明 ]:
Missing Phrase - N15.00950417-P261

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R22

[ 安全声明 (欧洲) ]:
26-45-36/37-16-7

[ 危险品运输编码 ]:
2490

[ RTECS号 ]:
KN1750000

[ 包装等级 ]:
II

[ 危险类别 ]:
6.1(a)

[ 海关编码 ]:
2909199012

二氯异乙醚合成路线

二氯异乙醚上下游产品

二氯异乙醚上游产品

二氯异乙醚下游产品

二氯异乙醚海关

[ 海关编码 ]: 2909199012

[ 中文概述 ]:
2909199012 二氯异丙醚。监管条件:S(进出口农药登记证明)。增值税率:17.0%。退税率:13.0%。最低关税:5.5%。普通关税:30.0%

[ Summary ]:
2909199012 1-chloro-2-((1-chloropropan-2-yl)oxy)propane。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:13.0%。MFN tarrif:5.5%。general tariff:30.0%

二氯异乙醚文献

bis(2-Chloro-1-methylethyl)ether.

IARC Monogr. Eval. Carcinog. Risk Chem. Hum. 41 , 149-60, (1986)

Bis(2-chloro-1-methylethyl)ether.

IARC Monogr. Eval. Carcinog. Risks Hum. 71 Pt 3 , 1275-9, (1999)

PCBs and DDE in tree swallow (Tachycineta bicolor) eggs and nestlings from an estuarine PCB superfund site, New Bedford Harbor, MA, U.S.A.

Environ. Sci. Technol. 43(21) , 8387-92, (2009)

While breeding tree swallows (Tachycineta bicolor) have been used as biomonitors for freshwater sites, we report the first use of this species to assess contaminant bioaccumulation from estuarine bree...

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