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3-硝基-4-氯苯甲醚

3-硝基-4-氯苯甲醚用途

【用途一】
用作医药、染料中间体

3-硝基-4-氯苯甲醚名称

[ CAS 号 ]:
10298-80-3

[ 中文名 ]:
4-氯-3-硝基苯甲醚

[ 英文名 ]:
4-Chloro-3-nitroanisole

[中文别名 ]:

[英文别名 ]:

4-chloro-3-nitrophenyl methyl ether
2-Chloro-5-Methoxynitrobenzene
1-Chloro-2-nitro-4-methoxybenzene
4-Chloro-3-nitroanisole
dioxoaMine
1-Chloro-4-methoxy-2-nitrobenzene
EINECS 233-674-1
4-methoxy-2-nitrochlorobenzene
2-fluoronitrobenzene
4-Chlor-3-nitro-anisol

3-硝基-4-氯苯甲醚物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
293.3±20.0 °C at 760 mmHg

[ 熔点 ]:
41-43 °C(lit.)

[ 分子式 ]:
C₇H₆ClNO₃

[ 分子量 ]:
187.580

[ 闪点 ]:
131.2±21.8 °C

[ 精确质量 ]:
187.003616

[ PSA ]:
55.05000

[ LogP ]:
2.65

[ 外观性状 ]:
淡奶油色干结晶粉末

[ 蒸汽压 ]:
0.0±0.6 mmHg at 25°C

[ 折射率 ]:
1.560

[ 储存条件 ]:
室温，密封，干燥

3-硝基-4-氯苯甲醚MSDS

3-硝基-4-氯苯甲醚毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BZ8580000

CHEMICAL NAME :: Anisole, 4-chloro-3-nitro-

CAS REGISTRY NUMBER :: 10298-80-3

BEILSTEIN REFERENCE NO. :: 0640872

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C7-H6-Cl-N-O3

MOLECULAR WEIGHT :: 187.59

WISWESSER LINE NOTATION :: WNR BG EO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#04759

3-硝基-4-氯苯甲醚安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
BZ8580000

[ 海关编码 ]:
29093090

3-硝基-4-氯苯甲醚合成路线

3-硝基-4-氯苯甲醚上下游产品

3-硝基-4-氯苯甲醚上游产品

3-硝基-4-氯苯甲醚下游产品

3-硝基-4-氯苯甲醚制备

【方法一】
以对氨基苯甲醚为原料，经氨基乙酰化保护、硝化、氨基脱保护、氯代合成10298-80-3（4-氯-3-硝基苯甲醚）。

3-硝基-4-氯苯甲醚海关

[ 海关编码 ]: 2909309090

[ 中文概述 ]:
2909309090 其他芳香醚及其卤化衍生物、磺化、硝化衍生物（包括亚硝化衍生物）。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:5.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

3-硝基-4-氯苯甲醚文献

Synthesis and antiinflammatory activity of 7-methanesulfonylamino-6-phenoxychromones. Antiarthritic effect of the 3-formylamino compound (T-614) in chronic inflammatory disease models.

Chem. Pharm. Bull. 48(1) , 131-9, (2000)

A group of derivatives of 7-methanesulfonylamino-6-phenoxychromone (1) at the pyrone and phenoxy rings was synthesized starting with 4-chloro-3-nitroanisole and evaluated against acute and chronic inf...

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