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2-甲基氨-5-氯二苯甲酮

2-甲基氨-5-氯二苯甲酮用途

(5-氯-2-(甲氨基)苯基)(苯基)甲酮是一种生物化学试剂,可作为生物材料或有机化合物用于生命科学相关研究。

2-甲基氨-5-氯二苯甲酮名称

[ CAS 号 ]:
1022-13-5

[ 中文名 ]:
2-甲氨基-5-氯二苯甲酮

[ 英文名 ]:
2-Methylamino-5-chlorobenzophenone

[中文别名 ]:

[英文别名 ]:

Ro 5-4365
2-METHYLAMINO-5-CHLORO BENZOPHENONE
Methyl-aMino ketone
2-Methylamino-5-chlorobenzophenone
Benzophenone,2-acetamido-5-chloro
EINECS 213-822-1
Methanone, [5-chloro-2-(methylamino)phenyl]phenyl-
Diazepam,acid hydrolyzed
Diazepam benzophenone
[5-Chloro-2-(methylamino)phenyl](phenyl)methanone

2-甲基氨-5-氯二苯甲酮生物活性

[ 描述 ]:

(5-氯-2-(甲氨基)苯基)(苯基)甲酮是一种生物化学试剂,可作为生物材料或有机化合物用于生命科学相关研究。

[ 相关类别 ]:

研究领域 >> 其他

[体外研究]

2个-甲氨基-5个-氯苯甲酮是二苯甲酮类的分析标准品。1,2,3 2-甲氨基-5个-氯苯甲酮是地西泮的代谢物,也被用作合成地西泮的合成中间体。在缴获的依替唑仑样品中发现了它本产品用于研究和法医应用。

[参考文献]

[1]. Jain, R.Simplified method for simultaneous determination of diazepam and its metabolites in urine by thin-layer chromatography and direct densitometryJ . Chromatogr .615(2)365-368(1993).

[2]. OlguÍn, HJ, GuzmÁn, DC, GarcÍa, EH, et al.Diazepam: Principal indications related with its molecular actions and advantagesDiazepam59-80(2014).

[3]. Downey, C. , O'Donnell, A., McLaughlin, G., et al.An unusual detection of 2-amino-3-(2-chlorobenzoyl)-5-ethylthiophene and 2-methylamino-5-chlorobenzophenone in illicit yellow etizolam tablets marked " 5617" seized in the Republic of Ireland Drug Test. Anal. (2021).

2-甲基氨-5-氯二苯甲酮物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
421.9±35.0 °C at 760 mmHg

[ 熔点 ]:
93-95 °C(lit.)

[ 分子式 ]:
C₁₄H₁₂ClNO

[ 分子量 ]:
245.71

[ 闪点 ]:
209.0±25.9 °C

[ 精确质量 ]:
245.060745

[ PSA ]:
29.10000

[ LogP ]:
4.66

[ 外观性状 ]:
黄色结晶粉末

[ 蒸汽压 ]:
0.0±1.0 mmHg at 25°C

[ 折射率 ]:
1.627

[ 储存条件 ]:
室温

[ 稳定性 ]:
Stable. Incompatible with strong oxidizing agents.

2-甲基氨-5-氯二苯甲酮MSDS

2-甲基氨-5-氯二苯甲酮毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DJ0414000

CHEMICAL NAME :: Benzophenone, 5-chloro-2-(methylamino)-

CAS REGISTRY NUMBER :: 1022-13-5

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C14-H12-Cl-N-O

MOLECULAR WEIGHT :: 245.72

2-甲基氨-5-氯二苯甲酮安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S37/39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
DJ0414000

[ 海关编码 ]:
2922399090

2-甲基氨-5-氯二苯甲酮合成路线

2-甲基氨-5-氯二苯甲酮上下游产品

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2-甲基氨-5-氯二苯甲酮下游产品

2-甲基氨-5-氯二苯甲酮海关

[ 海关编码 ]: 2922399090

[ 中文概述 ]:
2922399090 其他氨基醛、氨基酮及其盐（包括氨基醌及其盐，但含有一种以上含氧基的除外）. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ Summary ]:
2922399090 other amino-aldehydes, amino-ketones and amino-quinones, other than those containing more than one kind of oxygen function; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

2-甲基氨-5-氯二苯甲酮文献

Determination of hydrazine in pharmaceuticals IV: Hydrazine and benzylhydrazine in isocarboxazid.

J. Pharm. Sci. 74(1) , 105-7, (1985)

A GC procedure for the simultaneous determination of hydrazine and benzylhydrazine in isocarboxazid raw material and tablet formulations has been developed. The method is based on the reaction of benz...

[The preservability of sibazon breakdown products in the cadavers of experimental animals].

Sud. Med. Ekspert. 41(3) , 24-6, (1998)

Cibasone degradation products were measured in corpses of 15 cats poisoned with cibasone in a dose of 750 mg/kg. Cibasone was assessed by semiquantitative method on Silufol UV-254 plates from the cont...

Simplified method for simultaneous determination of diazepam and its metabolites in urine by thin-layer chromatography and direct densitometry.

J. Chromatogr. A. 615(2) , 365-8, (1993)

A direct densitometric method for determination of diazepam and its metabolites in urine was developed. The proposed procedure involves acid hydrolysis of urine specimens, thereby converting diazepam ...

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